I don’t really get what you mean with AGWN, is this simply that $n(t_i)$ are independent with $n(t_i) \sim N(0,\sigma^2)$? The least squares estimator (which, as usual with a normal model, coincide with maximum likelihood estimator, see eg [this answer](https://stats.stackexchange.com/a/12565/8076)) is easy to find with numerical methods, here is a piece of R code: a <- 2; b <- 0.2; c <- -1 t <- seq(-5,10, length=100) y <- a*exp(-b*t)+c+rnorm(length(t), sd=2) f <- function(par, t, y) { a <- par[1]; b <- par[2]; c <- par[3]; return(sum((a*exp(-b*t)+c-y)**2 ) ); } nlm( function(par) f(par, t, y), c(0,0,0)) The result of the last call is $minimum [1] 430.8242 $estimate [1] 2.0875336 0.1961210 -0.8672079 $gradient [1] 1.301591e-05 -2.745537e-05 2.603429e-05 $code [1] 1 $iterations [1] 19 Our initial values (2, 0.2, -1) are estimated by (2.088, 0.196, -0.867). You can get a plot of the data points, the "true model" (red line) and the estimated model (dotted red line) as follows: plot(t,y) lines( t, a*exp(-b*t)+c, col="red") nlm( function(par) f(par, t, y), c(0,0,0))$estimate -> r lines( t, r[1]*exp(-r[2]*t)+r[3], col="red", lty=2) ![Data points, with in red line the true model, in dotted red line the fitted model][1] Also, be sure not to miss [this related question](https://stats.stackexchange.com/questions/6720/estimation-of-exponential-model) already quoted by whuber in the comments. **A few hints for numerical optimization** In the above code the numerical optimization is done using `nlm`, a function of R. Here are a few hints for a more elementary solution. If $b\ne 0$ is fixed, it is easy to find $a$ and $c$ minimizing $f(a,b,c) = \sum_{i=1}^n (a \exp(-b\cdot t_i) +c -y_i)^2$: this a the classical least squares for the linear model. Namely, letting $x_i = \exp(-b\cdot t_i)$, we find $$ \begin{array}{rcccl} a &=& a(b) &=& { n \sum_i y_i x_i - \left( \sum_i y_i \right)\left(\sum_i x_i \right)\over n \sum x_i^2 - \left(\sum_i x_i \right)^2 }, \\ c &=& c(b) &=& { \sum_i y_i \sum_i x_i^2 - \left( \sum_i y_i x_i \right)\left(\sum_i x_i \right)\over n \sum x_i^2 - \left(\sum_i x_i \right)^2 }. \\ \end{array}$$ Then set $$ g(b) = f(a(b), b, c(b)).$$ The optimization problem is now reduced to find the minimum of $g(b)$. This can be done either using [Newton method](http://en.wikipedia.org/wiki/Newton%27s_method_in_optimization) or a [ternary search](http://en.wikipedia.org/wiki/Ternary_search). [1]: https://i.sstatic.net/L1Uui.png