I’ve been playing around with both `nlme::lme` and `lme4::lmer`. I fitted a simple random intercepts model using `lme()` and `lmer()`. As you can see below, I got completely different results from `lmer()` and `lme()`. Even signs of coefficients are different! Am I doing something wrong? I also fitted an empty model with two pakcages. In this case, the results were practically same (results not shwon). Would you educate me to understand this issue? Unless I made a mistake, I think there is something wrong with the lme4 package. Thank you. multi<-structure(list(x = c(4.9, 4.84, 4.91, 5, 4.95, 3.94, 3.88, 3.95, 4.04, 3.99, 2.97, 2.92, 2.99, 3.08, 3.03, 2.01, 1.96, 2.03, 2.12, 2.07, 1.05, 1, 1.07, 1.16, 1.11), y = c(3.2, 3.21, 3.256, 3.25, 3.256, 3.386, 3.396, 3.442, 3.436, 3.442, 3.572, 3.582, 3.628, 3.622, 3.628, 3.758, 3.768, 3.814, 3.808, 3.814, 3.944, 3.954, 4, 3.994, 4), pid = 1:25, gid = c(1L, 1L, 1L, 1L, 1L, 2L, 2L, 2L, 2L, 2L, 3L, 3L, 3L, 3L, 3L, 4L, 4L, 4L, 4L, 4L, 5L, 5L, 5L, 5L, 5L)), class = "data.frame", row.names = c(NA, -25L)) #lme > lme(y~x, random=~1|gid,data=multi,method="REML") Linear mixed-effects model fit by REML Data: multi Log-restricted-likelihood: 41.76745 Fixed: y ~ x (Intercept) x 4.1846756 -0.1928357 #lmer lmer(y~x+(1|(gid)), data=multi, REML=T) Linear mixed model fit by REML ['lmerMod'] Formula: y ~ x + (1 | (gid)) Data: multi REML criterion at convergence: -78.4862 Random effects: Groups Name Std.Dev. (gid) (Intercept) 0.70325 Residual 0.02031 Number of obs: 25, groups: (gid), 5 Fixed Effects: (Intercept) x 2.8152 0.2638 [1]: https://i.sstatic.net/l4WPG.png