I get enormous coefficients during logistic regression, see coefficients with `krajULKV`:

    > summary(m5)
    
    Call:
    glm(formula = cbind(ml, ad) ~ rok + obdobi + kraj + resid_usili2 + 
        rok:obdobi + rok:kraj + obdobi:kraj + kraj:resid_usili2 + 
        rok:obdobi:kraj, family = "quasibinomial")
    
    Deviance Residuals: 
        Min       1Q   Median       3Q      Max  
    -2.7796  -1.0958  -0.3101   1.0034   2.8370  
    
    Coefficients:
                                  Estimate     Std. Error t value Pr(>|t|)   
    (Intercept)                 -486.72087      664.71911  -0.732  0.46424   
    rok                            0.24232        0.33114   0.732  0.46452   
    obdobinehn                  3400.43703     1354.14874   2.511  0.01223 * 
    krajJHC                      786.22409      708.50291   1.110  0.26746   
    krajJHM                      511.85538      823.03038   0.622  0.53417   
    krajLBK                      -23.94180     2388.86316  -0.010  0.99201   
    krajMSK                     1281.88767      955.09736   1.342  0.17992   
    krajOLK                     -175.19425     1255.82946  -0.140  0.88909   
    krajPAK                      349.76438     1071.03364   0.327  0.74408   
    krajPLK                    -1335.73206     1534.09899  -0.871  0.38418   
    krajSTC                      868.99157      692.30426   1.255  0.20976   
    krajULKV                  245661.86828 17496742.31677   0.014  0.98880   
    krajVYS                     3341.76686     1314.77140   2.542  0.01121 * 
    krajZLK                     3950.75617     2922.25220   1.352  0.17676   
    resid_usili2                  -1.44719        0.89315  -1.620  0.10555   
    rok:obdobinehn                -1.69479        0.67462  -2.512  0.01219 * 
    rok:krajJHC                   -0.39108        0.35295  -1.108  0.26817   
    rok:krajJHM                   -0.25481        0.40997  -0.622  0.53443   
    rok:krajLBK                    0.01621        1.19155   0.014  0.98915   
    rok:krajMSK                   -0.63985        0.47592  -1.344  0.17917   
    rok:krajOLK                    0.08714        0.62545   0.139  0.88923   
    rok:krajPAK                   -0.17419        0.53344  -0.327  0.74410   
    rok:krajPLK                    0.66539        0.76383   0.871  0.38394   
    rok:krajSTC                   -0.43292        0.34490  -1.255  0.20976   
    rok:krajULKV                -122.01076     8704.03367  -0.014  0.98882   
    rok:krajVYS                   -1.66391        0.65468  -2.542  0.01122 * 
    rok:krajZLK                   -1.96718        1.45474  -1.352  0.17667   
    obdobinehn:krajJHC         -3623.86807     1385.86009  -2.615  0.00909 **
    obdobinehn:krajJHM         -3220.08906     1458.83842  -2.207  0.02757 * 
    obdobinehn:krajLBK         -1051.07131     3434.11845  -0.306  0.75963   
    obdobinehn:krajMSK         -6415.65781     1978.30260  -3.243  0.00123 **
    obdobinehn:krajOLK         -2427.66591     1777.51914  -1.366  0.17239   
    obdobinehn:krajPAK         -3111.45312     1623.59145  -1.916  0.05566 . 
    obdobinehn:krajPLK         -1800.26258     2065.74461  -0.871  0.38375   
    obdobinehn:krajSTC         -4409.45624     1379.64196  -3.196  0.00145 **
    obdobinehn:krajULKV      -187832.68360 16454272.74951  -0.011  0.99089   
    obdobinehn:krajVYS         -5445.51446     1791.38012  -3.040  0.00244 **
    obdobinehn:krajZLK         -6216.43343     3167.49836  -1.963  0.05003 . 
    krajJHC:resid_usili2           1.60474        0.98554   1.628  0.10385   
    krajJHM:resid_usili2           1.57822        1.04518   1.510  0.13143   
    krajLBK:resid_usili2          11.53462       13.40012   0.861  0.38961   
    krajMSK:resid_usili2          -1.33600        1.55241  -0.861  0.38971   
    krajOLK:resid_usili2           0.07296        1.27034   0.057  0.95421   
    krajPAK:resid_usili2           1.35880        1.23033   1.104  0.26974   
    krajPLK:resid_usili2           1.90189        1.41163   1.347  0.17826   
    krajSTC:resid_usili2           2.05237        0.95972   2.139  0.03277 * 
    krajULKV:resid_usili2        599.79215    20568.86123   0.029  0.97674   
    krajVYS:resid_usili2           3.03834        1.16464   2.609  0.00925 **
    krajZLK:resid_usili2           1.18574        1.11024   1.068  0.28583   
    rok:obdobinehn:krajJHC         1.80611        0.69042   2.616  0.00906 **
    rok:obdobinehn:krajJHM         1.60475        0.72676   2.208  0.02751 * 
    rok:obdobinehn:krajLBK         0.52268        1.71244   0.305  0.76027   
    rok:obdobinehn:krajMSK         3.19712        0.98564   3.244  0.00123 **
    rok:obdobinehn:krajOLK         1.21012        0.88541   1.367  0.17208   
    rok:obdobinehn:krajPAK         1.55034        0.80886   1.917  0.05563 . 
    rok:obdobinehn:krajPLK         0.89718        1.02893   0.872  0.38349   
    rok:obdobinehn:krajSTC         2.19742        0.68732   3.197  0.00144 **
    rok:obdobinehn:krajULKV       93.43130     8189.24994   0.011  0.99090   
    rok:obdobinehn:krajVYS         2.71357        0.89236   3.041  0.00243 **
    rok:obdobinehn:krajZLK         3.09624        1.57711   1.963  0.04996 * 
    ---
    Signif. codes:  0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1 
    
    (Dispersion parameter for quasibinomial family taken to be 1.258421)
    
        Null deviance: 1518.0  on 878  degrees of freedom
    Residual deviance: 1228.6  on 819  degrees of freedom
      (465 observations deleted due to missingness)
    AIC: NA
    
    Number of Fisher Scoring iterations: 18

**What does this mean??** Does it mean some multicollinearity, like @Scortchi meantioned in [this discussion](http://stats.stackexchange.com/q/48688/5509)? Or does this mean overfitting? How to detect the problem? **What shall I do now?**

I tried to remove some variables. This helps a bit but not so much:


    > m6 <- update(m5, ~.- kraj:resid_usili2)
    > m7 <- update(m6, ~.- resid_usili2)
    > summary(m7)
    
    Call:
    glm(formula = cbind(ml, ad) ~ rok + obdobi + kraj + rok:obdobi + 
        rok:kraj + obdobi:kraj + rok:obdobi:kraj, family = "quasibinomial")
    
    Deviance Residuals: 
        Min       1Q   Median       3Q      Max  
    -2.9098  -1.1931  -0.2274   1.0529   3.1283  
    
    Coefficients:
                               Estimate  Std. Error t value Pr(>|t|)
    (Intercept)              -118.95199   476.34698  -0.250    0.803
    rok                         0.05971     0.23718   0.252    0.801
    obdobinehn                412.69412   646.95083   0.638    0.524
    krajJHC                   447.69791   498.45358   0.898    0.369
    krajJHM                   -62.92516   525.85737  -0.120    0.905
    krajLBK                   677.73239  1595.20024   0.425    0.671
    krajMSK                   278.24639   621.32312   0.448    0.654
    krajOLK                  -705.97832   782.53474  -0.902    0.367
    krajPAK                   387.96543   608.98961   0.637    0.524
    krajPLK                  -653.68419   782.20737  -0.836    0.403
    krajSTC                  -114.34822   489.06318  -0.234    0.815
    krajULKV                -2117.64674  1797.75836  -1.178    0.239
    krajVYS                   884.74411   681.05324   1.299    0.194
    krajZLK                  -997.77613   925.93280  -1.078    0.281
    rok:obdobinehn             -0.20602     0.32211  -0.640    0.523
    rok:krajJHC                -0.22303     0.24819  -0.899    0.369
    rok:krajJHM                 0.03092     0.26180   0.118    0.906
    rok:krajLBK                -0.33909     0.79438  -0.427    0.670
    rok:krajMSK                -0.13889     0.30935  -0.449    0.654
    rok:krajOLK                 0.35102     0.38943   0.901    0.368
    rok:krajPAK                -0.19392     0.30323  -0.640    0.523
    rok:krajPLK                 0.32463     0.38937   0.834    0.405
    rok:krajSTC                 0.05677     0.24351   0.233    0.816
    rok:krajULKV                1.05287     0.89453   1.177    0.239
    rok:krajVYS                -0.44149     0.33911  -1.302    0.193
    rok:krajZLK                 0.49612     0.46081   1.077    0.282
    obdobinehn:krajJHC       -776.31258   672.68911  -1.154    0.249
    obdobinehn:krajJHM       -267.78650   700.38741  -0.382    0.702
    obdobinehn:krajLBK      -1246.67321  1760.37329  -0.708    0.479
    obdobinehn:krajMSK       -383.77613   858.81391  -0.447    0.655
    obdobinehn:krajOLK        -96.72334   947.75189  -0.102    0.919
    obdobinehn:krajPAK       -540.25140   827.13134  -0.653    0.514
    obdobinehn:krajPLK       -517.49161  1124.63474  -0.460    0.645
    obdobinehn:krajSTC       -683.81160   672.66674  -1.017    0.310
    obdobinehn:krajULKV      2344.32314  2073.98366   1.130    0.259
    obdobinehn:krajVYS       -795.62043   917.80551  -0.867    0.386
    obdobinehn:krajZLK        618.33075  1093.37768   0.566    0.572
    rok:obdobinehn:krajJHC      0.38725     0.33493   1.156    0.248
    rok:obdobinehn:krajJHM      0.13374     0.34870   0.384    0.701
    rok:obdobinehn:krajLBK      0.62237     0.87662   0.710    0.478
    rok:obdobinehn:krajMSK      0.19114     0.42758   0.447    0.655
    rok:obdobinehn:krajOLK      0.04842     0.47171   0.103    0.918
    rok:obdobinehn:krajPAK      0.26922     0.41184   0.654    0.513
    rok:obdobinehn:krajPLK      0.25790     0.55986   0.461    0.645
    rok:obdobinehn:krajSTC      0.34078     0.33492   1.017    0.309
    rok:obdobinehn:krajULKV    -1.16571     1.03236  -1.129    0.259
    rok:obdobinehn:krajVYS      0.39675     0.45704   0.868    0.386
    rok:obdobinehn:krajZLK     -0.30732     0.54422  -0.565    0.572
    
    (Dispersion parameter for quasibinomial family taken to be 1.313286)
    
        Null deviance: 2396.8  on 1343  degrees of freedom
    Residual deviance: 2110.3  on 1296  degrees of freedom
    AIC: NA
    
    Number of Fisher Scoring iterations: 5