There are several "flavours" or forms of the bootstrap (e.g. non-parametric, parametric, residual resampling and many more). The bootstrap in the example is called a **non-parametric bootstrap**, or **case resampling** (see [here][1], [here][2], [here][3] and [here][6] for applications in regression). The basic idea is that you treat your sample as population and repeatedly draw new samples from it **with replacement**. All original observations have equal probability of being drawn into the new sample. Then you calculate and store the statistic(s) of interest, this may be the mean, the median or regression coefficients **using the newly drawn sample**. This is repeated $n$ times. In each iteration, some observations from your original sample are drawn multiple times while some observations may not be drawn at all. After $n$ iterations, you have $n$ stored bootstrap estimates of the statistic(s) of interest (e.g. if $n=1000$ and the statistic of interest is the mean, you have 1000 bootstrapped estimates of the mean). Lastly, summary statistics such as the mean, median and the standard deviation of the $n$ bootstrap-estimates are calculated. Bootstrapping is often used for: 1. Calculation of confidence intervals (and estimation of the standard errors) 2. Estimation of the bias of the point estimates There are [several methods][4] for calculating confidence intervals based on the bootstrap samples ([this paper][5] provides explanation and guidance). One very simple method is just calculating the 2.5th and 97.5th percentiles of the bootstrap samples (see code below). The bias is simply estimated as the difference between the bootstrap samples and the original estimates. Let's replicate the example from the website but using our own loop incorporating the ideas I've outlined above (drawing repeadetly with replacement): #----------------------------------------------------------------------------- # Load packages #----------------------------------------------------------------------------- require(ggplot2) require(pscl) require(MASS) require(boot) #----------------------------------------------------------------------------- # Load data #----------------------------------------------------------------------------- zinb <- read.csv("http://www.ats.ucla.edu/stat/data/fish.csv") zinb <- within(zinb, { nofish <- factor(nofish) livebait <- factor(livebait) camper <- factor(camper) }) #----------------------------------------------------------------------------- # Calculate zero-inflated regression #----------------------------------------------------------------------------- m1 <- zeroinfl(count ~ child + camper | persons, data = zinb, dist = "negbin", EM = TRUE) #----------------------------------------------------------------------------- # Store the original regression coefficients #----------------------------------------------------------------------------- original.estimates <- as.vector(t(do.call(rbind, coef(summary(m1)))[, 1:2])) #----------------------------------------------------------------------------- # Set the number of replications #----------------------------------------------------------------------------- n.sim <- 2000 #----------------------------------------------------------------------------- # Set up a matrix to store the results #----------------------------------------------------------------------------- store.matrix <- matrix(NA, nrow=n.sim, ncol=12) #----------------------------------------------------------------------------- # The loop #----------------------------------------------------------------------------- set.seed(123) for(i in 1:n.sim) { #----------------------------------------------------------------------------- # Draw the observations WITH replacement #----------------------------------------------------------------------------- data.new <- zinb[sample(1:dim(zinb)[1], dim(zinb)[1], replace=TRUE),] #----------------------------------------------------------------------------- # Calculate the model with this "new" data #----------------------------------------------------------------------------- m <- zeroinfl(count ~ child + camper | persons, data = data.new, dist = "negbin", start = list(count = c(1.3711, -1.5152, 0.879), zero = c(1.6028, -1.6663))) #----------------------------------------------------------------------------- # Store the results #----------------------------------------------------------------------------- store.matrix[i, ] <- as.vector(t(do.call(rbind, coef(summary(m)))[, 1:2])) } #----------------------------------------------------------------------------- # Save the means, medians and SDs of the bootstrapped statistics #----------------------------------------------------------------------------- boot.means <- colMeans(store.matrix, na.rm=T) boot.medians <- apply(store.matrix,2,median, na.rm=T) boot.sds <- apply(store.matrix,2,sd, na.rm=T) #----------------------------------------------------------------------------- # The bootstrap bias is the difference between the mean bootstrap estimates # and the original estimates #----------------------------------------------------------------------------- boot.bias <- colMeans(store.matrix, na.rm=T) - original.estimates #----------------------------------------------------------------------------- # Quantile confidence intervals #----------------------------------------------------------------------------- conf.mat <- matrix(apply(store.matrix, 2 ,quantile, c(0.025, 0.975), na.rm=T),ncol=2) colnames(conf.mat) <- c("95%-CI Lower", "95%-CI Upper") And here is our summary table: #----------------------------------------------------------------------------- # Set up summary data frame #----------------------------------------------------------------------------- summary.frame <- data.frame(mean=boot.means, median=boot.medians, sd=boot.sds, bias=boot.bias, "CI_lower"=conf.mat[,1], "CI_upper"=conf.mat[,2]) summary.frame mean median sd bias CI_lower CI_upper 1 1.2997903 1.3013079 0.39673804 -0.0712912250 0.51960031 -1.3066351 2 0.2526688 0.2485721 0.03207790 -0.0034460509 2.06049015 -0.4379761 3 -1.5661686 -1.5571989 0.26220013 -0.0509238534 0.19897759 0.1449354 4 0.2004957 0.1986454 0.01949437 0.0049018955 0.32294130 0.2140118 5 0.9543834 0.9252035 0.48914523 0.0753405152 -2.12899783 0.4414957 6 0.2702361 0.2688095 0.02042504 0.0009582592 -1.09195998 8.0471143 7 -0.8996836 -0.9082379 0.22173921 0.0856792712 0.16744198 0.5811394 8 0.1788934 0.1781161 0.01667250 0.0029512565 0.24179778 57.6416680 9 2.0682618 1.7718903 1.59102322 0.4654897865 0.03492612 -8.4344038 10 4.0208757 0.8269775 13.23433539 3.1845709680 1.90245108 -1.1156127 11 -2.0969405 -1.6717102 1.56310762 -0.4306843771 0.23271566 0.3363101 12 3.8660345 0.6434859 13.27525033 3.1870641941 0.31370593 57.6061993 **Some explanations** - The difference between the mean of the bootstrap estimates and the original estimates is what is called "bias" in the output of `boot` - What the output of `boot` calls "std. error" is the standard deviation of the bootstrapped estimates Compare it with the output from `boot`: #----------------------------------------------------------------------------- # Compare with boot output #----------------------------------------------------------------------------- set.seed(10) res <- boot(zinb, f, R = 2000, parallel = "snow", ncpus = 4) res Bootstrap Statistics : original bias std. error t1* 1.3710504 -0.076735010 0.39842905 t2* 0.2561136 -0.003127401 0.03172301 t3* -1.5152609 -0.064110745 0.26554358 t4* 0.1955916 0.005819378 0.01933571 t5* 0.8790522 0.083866901 0.49476780 t6* 0.2692734 0.001475496 0.01957823 t7* -0.9853566 0.083186595 0.22384444 t8* 0.1759504 0.002507872 0.01648298 t9* 1.6031354 0.482973831 1.58603356 t10* 0.8365225 3.240981223 13.86307093 t11* -1.6665917 -0.453059768 1.55143344 t12* 0.6793077 3.247826469 13.90167954 #----------------------------------------------------------------------------- # Our summary table #----------------------------------------------------------------------------- summary.frame mean median sd bias CI_lower CI_upper 1 1.2997903 1.3013079 0.39673804 -0.0712912250 0.51960031 -1.3066351 2 0.2526688 0.2485721 0.03207790 -0.0034460509 2.06049015 -0.4379761 3 -1.5661686 -1.5571989 0.26220013 -0.0509238534 0.19897759 0.1449354 4 0.2004957 0.1986454 0.01949437 0.0049018955 0.32294130 0.2140118 5 0.9543834 0.9252035 0.48914523 0.0753405152 -2.12899783 0.4414957 6 0.2702361 0.2688095 0.02042504 0.0009582592 -1.09195998 8.0471143 7 -0.8996836 -0.9082379 0.22173921 0.0856792712 0.16744198 0.5811394 8 0.1788934 0.1781161 0.01667250 0.0029512565 0.24179778 57.6416680 9 2.0682618 1.7718903 1.59102322 0.4654897865 0.03492612 -8.4344038 10 4.0208757 0.8269775 13.23433539 3.1845709680 1.90245108 -1.1156127 11 -2.0969405 -1.6717102 1.56310762 -0.4306843771 0.23271566 0.3363101 12 3.8660345 0.6434859 13.27525033 3.1870641941 0.31370593 57.6061993 Compare the "bias" columns and the "std. error" with the "sd" column of our own summary table. [1]: http://www.stat.cmu.edu/~cshalizi/402/lectures/08-bootstrap/lecture-08.pdf [2]: http://bcs.whfreeman.com/ips5e/content/cat_080/pdf/moore14.pdf [3]: http://en.wikipedia.org/wiki/Bootstrapping_(statistics)#Case_resampling [4]: http://en.wikipedia.org/wiki/Bootstrapping_(statistics)#Deriving_confidence_intervals_from_the_bootstrap_distribution [5]: http://onlinelibrary.wiley.com/doi/10.1002/(SICI)1097-0258(20000515)19:9%3C1141::AID-SIM479%3E3.0.CO;2-F/abstract;jsessionid=2969C4F4A320EA6AEE19776DE70D4A5B.d02t04 [6]: http://socserv.mcmaster.ca/jfox/Books/Companion/appendix/Appendix-Bootstrapping.pdf