How to sample from a given univariate CDF is a huge subject, so I will assume that part of the answer is known and will address how to find the conditional CDF from the copula. ---- By definition, any copula assigns probabilities to rectangular regions (within the unit square) delimited on the right by its first argument and above by its second argument. In particular, when $U$ and $V$ are uniformly distributed with $C$ as the copula for $(U,V)$ and $0 \lt \epsilon \le 1 - u$ is sufficiently small, $$\eqalign{ \Pr(U\in (u, u+\epsilon]\text{ and }V \le v) &= \Pr(U\le u+\epsilon, V \le v) - \Pr(U\le u, V \le v) \\ &=C(u+\epsilon, v) - C(u, v). }$$ Therefore, the conditional cumulative distribution function ought to arise as the (right-hand) limiting value of $$\Pr(U\in (u, u+\epsilon]\text{ and }V \le v\,\Big|\,U\in (u, u+\epsilon]) = \frac{C(u+\epsilon, v) - C(u, v)}{\epsilon}.$$ Provided this limit exists (which it will almost everywhere for $u$), by definition it is the first partial derivative, $\partial C(u,v)/\partial u$. This, therefore, gives the conditional CDF for $V\,\Big|\, U=u$ evaluated at $v$. ![Figure][1] *The left figure shows a contour plot of the copula (representing a surface) $C(u,v)=uv/(u+v-uv)$. The right figure is the graph of the conditional distribution of $V$ for $u\approx 0.23$. It is a cross section of the rightward slope of the surface.* --- ###Reference### Roger B. Nelsen, *An Introduction to Copulas,* Second Edition. Springer 2006: Section 2.9, *Random Variate Generation.* [1]: https://i.sstatic.net/9avhs.png