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Methods focused on contrasting and combining results from different studies, in the hope of increasing precision and external validity.

3 votes
1 answer
4k views

Orwin's fail safe N test

In Orwin's fail safe N test how to decide the values of criterion for a trivial log odd's ratio and mean log odds ratio in missing studies. I am a medical doctor. Please tell me in simple english. The …
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  • 949
1 vote
1 answer
2k views

Interpret residuals in random and fixed effects models in meta-analysis

How to interpret residuals in random and fixed effects models? I am a medical doctor. Kindly explain in simple words. Updated Here is an example: Weight (Fixed) Weight (Random) Residual (Fixe …
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  • 949
5 votes
1 answer
146 views

Meta-analysis of 3 regions' data for 5 years

Can we do a meta-analysis of data of 3 regions. A particular disease was treated with the same treatment but implemented thoroughly in 2 regions and not so thoroughly in 1 region. How to proceed with …
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  • 949
4 votes
2 answers
15k views

Egger’s linear regression method intercept in meta analysis

In Meta analysis, how to interpret the Egger’s linear regression method intercept (B0) 10.34631, 95% confidence interval (1.05905, 19.63357), with t=3.54535, df=3. The 1-tailed p-value (recommended) i …
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  • 949
3 votes
1 answer
164 views

How to assess drug effects using annual death rate data?

I am planning a study to collect data of patients dying after brain infection versus number of cases for the next 5 years in 2 cities where they manage the disease with different drugs. Will a year …
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  • 949
4 votes
3 answers
464 views

How to assess effect of intervention in one state versus another using annual death rate data?

I am a beginner in statistics. I have these unpublished data (cases and deaths) of a disease for 7 years (2004-2010) from 2 neighbouring states. The study was started in 2004. State 1 and State 2 rece …
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  • 949