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The science of statistics applied to the analysis of biological or medical data.

0 votes
0 answers
110 views

Model is nearly unidentifiable: large eigenvalue ratio in mixed logistic model

I am investigating effect of various "treatments" on various disease outcomes with univariate mixed logistic regression models corrected for covariates: f1 <- as.formula(paste(disease, "~ age + ", t, …
JED HK's user avatar
  • 409
19 votes
3 answers
2k views

Widespread overfitting in health domain research?

I was reading about flaws with model selection techniques such as elimination based on significance and backwards selection via AIC (or similar) in the context of regression leading to inflated coeffi …
JED HK's user avatar
  • 409