6
votes
Accepted
What is the rationale for computing a confidence interval in a study that won't or can't be repeated?
Here is a quote from Larry Wasserman's book "All of statistics"$^{[1]}$ that offers a different perspective on the topic. On page 92, he writes:
Some texts interpret confidence intervals as ...
6
votes
For normality testing, should biological replicates be averaged or should all values of each subgroup be evaluated as independent data points?
Choosing whether to do a parametric or non-parametric test based on an initial assessment of normality is not good practice. See this page for extensive discussion. Even if you were to evaluate ...
5
votes
For normality testing, should biological replicates be averaged or should all values of each subgroup be evaluated as independent data points?
"Replicates" in bioassays are usually used as a method for reducing measurement noise, and sometimes as a way to decide on whether a run of the assay was a technical success. The variation ...
3
votes
What is the rationale for computing a confidence interval in a study that won't or can't be repeated?
Actually, I think the rationale here:
Is there a (scientific) rationale to compute a confidence interval in a study that won't or can't be repeated exactly?
Makes it more necessary that the CI is ...
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