6 votes
Accepted

What is the rationale for computing a confidence interval in a study that won't or can't be repeated?

Here is a quote from Larry Wasserman's book "All of statistics"$^{[1]}$ that offers a different perspective on the topic. On page 92, he writes: Some texts interpret confidence intervals as ...
COOLSerdash's user avatar
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6 votes

For normality testing, should biological replicates be averaged or should all values of each subgroup be evaluated as independent data points?

Choosing whether to do a parametric or non-parametric test based on an initial assessment of normality is not good practice. See this page for extensive discussion. Even if you were to evaluate ...
EdM's user avatar
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5 votes

For normality testing, should biological replicates be averaged or should all values of each subgroup be evaluated as independent data points?

"Replicates" in bioassays are usually used as a method for reducing measurement noise, and sometimes as a way to decide on whether a run of the assay was a technical success. The variation ...
Michael Lew's user avatar
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3 votes

What is the rationale for computing a confidence interval in a study that won't or can't be repeated?

Actually, I think the rationale here: Is there a (scientific) rationale to compute a confidence interval in a study that won't or can't be repeated exactly? Makes it more necessary that the CI is ...
Shawn Hemelstrand's user avatar

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