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Jan 5, 2016 at 17:20 comment added user32398 You could just run ANOVA, and then use a modified Type I error level (Bonferroni or Sidak $\alpha^* = \alpha /\#tests$) as the p-value criterion, or use Benjamini-Hochberg FDR. From a machine learning perspective, straightforward inferential hypothesis testing won't cut it alone -- you'd have to use CV at every step.
Jan 5, 2016 at 16:02 comment added Ellis Valentiner @LEP I expect that the clusters within each group will differ – so I expect that the ANOVA will nearly always be "significant".
Jan 5, 2016 at 15:40 comment added user32398 Regarding CV during ANOVA, if you randomly generated 100 values of a variate in 3 groups, and ran ANOVA to determine if the three averages (based on $n=100$ in each group) are significantly different you can obtain significance by chance alone. However, if you e.g. sampled 20%,30%,40%, or 50% of the objects from each group and ran ANOVA on the smaller sample sizes, then kept a running average of -log(p-value) for every fold and repeated this, say, 10 times, you could minimize chances of a obtaining significant results by chance alone.
Jan 5, 2016 at 15:35 comment added user32398 Sure, one-way ANOVA will work, but recall that will only address one feature across all the groups (univariate). You could test many of the same features across many groups using a Hotelling test (MANOVA). Also, through chance alone, you could get significantly different means, so you'd need to partition to objects in each group into folds (cross-validation) and then keep an average value of e.g. -log(p-value).
Jan 5, 2016 at 15:19 comment added Ellis Valentiner @LEP I am thinking that the clustering aspect is less important and the comparison of the groups is more so. Can I just do a one-way anova for each group?
Jan 5, 2016 at 14:24 comment added user32398 After clustering within a group, you could calculate several cluster quality indicators (silhouette index, Dunn's index, Davies-Bouldin index, Hubert's $\Gamma$), and then compare these across groups.
Jan 5, 2016 at 13:41 comment added Ellis Valentiner @DavidG.Stork the purpose is to reduce the information in each "group" by "prototypes" (i.e. clusters) and to then compare the groups in terms of their prototypes.
Jan 5, 2016 at 10:10 history edited Has QUIT--Anony-Mousse CC BY-SA 3.0
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Jan 5, 2016 at 1:00 comment added David G. Stork What is the purpose of your analysis? Are you trying to find the group with the greatest inter-group variation?
Jan 4, 2016 at 23:05 history asked Ellis Valentiner CC BY-SA 3.0