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Jan 31, 2017 at 17:34 history edited kjetil b halvorsen CC BY-SA 3.0
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Mar 28, 2016 at 17:46 vote accept John
Mar 28, 2016 at 12:14 comment added Wolfgang Ok, makes sense now. And I just found the time to write up an answer. So, actually, I need to recall my initial suggestion to consider methods described under the link I posted and instead approach this in the way described under my answer. Thank you for raising some doubts about my initial suggestion and drawing out the crucial distinction.
Mar 28, 2016 at 12:08 answer added Wolfgang timeline score: 2
Mar 26, 2016 at 16:26 history edited John CC BY-SA 3.0
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Mar 26, 2016 at 16:23 comment added Wolfgang Thanks. I assume the study variable is supposed to be 1,1,2,2 (and not 1,2,1,2 as it is right now), right?
Mar 26, 2016 at 15:50 comment added John Thank you @Wolfgang. I have amended the question to included example data, as requested.
Mar 26, 2016 at 15:48 history edited John CC BY-SA 3.0
To provide example data required for problem solution.
Mar 26, 2016 at 14:38 comment added Wolfgang I see. In that case, it would be better to compute the difference between the two log(RRs) (for older/younger) within the two studies and then pool those values to see if the pooled difference is significantly different from zero. If I understand you correctly, there are only 4 RRs here (two studies, with two subgroups each) -- so if you could add those RRs (and 95% CIs) to your question, I can show you how to do this.
Mar 26, 2016 at 9:13 comment added John Thank you @Wolfgang. Your link contains everything that I need to do the test. I just wanted to double check that it is OK to use the (Separate Meta-Analyses) method in my situation. In your example, you compare completely separate studies (i.e. with different alloc), whereas I compare subgroups (i.e. either older or younger than 50) from the same studies (different participants in the subgroups but taken from the same studies). I am just worried that my subgroups are not independent in the same way that your studies are (given within study effects).
Mar 5, 2016 at 15:56 comment added Wolfgang I don't have the time right now to turn this into a complete answer, but basically everything you are asking about is covered here: metafor-project.org/doku.php/…
Mar 4, 2016 at 13:16 answer added mdewey timeline score: 1
Mar 4, 2016 at 11:40 history asked John CC BY-SA 3.0