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Max Gordon
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Thought I just add to this topic that you might be interested in quantile regression with censoring. Bottai & Zhang 2010 proposed a "Laplace Regression" that can do just this task, you can find a PDF on this here. There is a package for Stata for this, it has yet not been translated to R although the quantreg package in R has a function for censored quantile regression, crq, that could be an option.

I think the approach is very interesting and might be much more intuitive to patients that hazards ratios. Knowing for instance that you have a 50 % chance of surviving additionalon the drug survive 2 more months given youthan ones that don't take the drug althoughand the side effects force you to stay 1-2 months at the hospital ismight make the choice of treatment much easier to understand.

Thought I just add to this topic that you might be interested in quantile regression with censoring. Bottai & Zhang 2010 proposed a "Laplace Regression" that can do just this task, you can find a PDF on this here. There is a package for Stata for this, it has yet not been translated to R although the quantreg package in R has a function for censored quantile regression, crq, that could be an option.

I think the approach is very interesting and might be much more intuitive to patients that hazards ratios. Knowing for instance that you have a 50 % chance of surviving additional 2 months given you take the drug although the side effects force you to stay 1-2 months at the hospital is much easier to understand.

Thought I just add to this topic that you might be interested in quantile regression with censoring. Bottai & Zhang 2010 proposed a "Laplace Regression" that can do just this task, you can find a PDF on this here. There is a package for Stata for this, it has yet not been translated to R although the quantreg package in R has a function for censored quantile regression, crq, that could be an option.

I think the approach is very interesting and might be much more intuitive to patients that hazards ratios. Knowing for instance that 50 % on the drug survive 2 more months than ones that don't take the drug and the side effects force you to stay 1-2 months at the hospital might make the choice of treatment much easier.

Source Link
Max Gordon
  • 6k
  • 8
  • 35
  • 52

Thought I just add to this topic that you might be interested in quantile regression with censoring. Bottai & Zhang 2010 proposed a "Laplace Regression" that can do just this task, you can find a PDF on this here. There is a package for Stata for this, it has yet not been translated to R although the quantreg package in R has a function for censored quantile regression, crq, that could be an option.

I think the approach is very interesting and might be much more intuitive to patients that hazards ratios. Knowing for instance that you have a 50 % chance of surviving additional 2 months given you take the drug although the side effects force you to stay 1-2 months at the hospital is much easier to understand.