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user88
user88

LASSO - variable Variable selection with LASSO

I am trying to fit a predictive gene-based model in survival analysis. My question is:

canCan I use LASSO as a variable selection method, and then run a multivariate coxCox regression to get the coefficients of those variables (genes) instead of using the coefficients from LASSO?

In that case (if I run a multivariate coxCox regression), I can get p-values, and make an inference for the coefficients.

I am pretty new to this area. Please bear with me if my questions are a bit dumb.

LASSO - variable selection

I am trying to fit a predictive gene-based model in survival analysis. My question is:

can I use LASSO as a variable selection method, and then run a multivariate cox regression to get the coefficients of those variables (genes) instead of using the coefficients from LASSO?

In that case (if I run a multivariate cox regression), I can get p-values, and make an inference for the coefficients.

I am pretty new to this area. Please bear with me if my questions are a bit dumb.

Variable selection with LASSO

I am trying to fit a predictive gene-based model in survival analysis. My question is:

Can I use LASSO as a variable selection method, and then run a multivariate Cox regression to get the coefficients of those variables (genes) instead of using the coefficients from LASSO?

In that case (if I run a multivariate Cox regression), I can get p-values, and make an inference for the coefficients.

I am pretty new to this area. Please bear with me if my questions are a bit dumb.

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gung - Reinstate Monica
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I am trying to findfit a predictive gene-based model in survival analysis.

  My question is:

can I use LASSO as a variable selection method, and then run a multivariate cox regression to get the coefficients of those variables (genes) instead of using the coefficients from LASSO?can I use LASSO as a variable selection method, and then run a multivariate cox regression to get the coefficients of those variables (genes) instead of using the coefficients from LASSO?

In that case (if I run a multivariate cox regression), I can get p values-values, and make an inference for the coefficients.

I am pretty new to this area. pleasePlease bear with me if my questions are a bit dumb.

Thank you.

I am trying to find a predictive gene-based model in survival analysis.

  My question is

can I use LASSO as a variable selection method, and then run a multivariate cox regression to get the coefficients of those variables (genes) instead of using the coefficients from LASSO?

In that case (if I run a multivariate cox regression), I can get p values, and make an inference for the coefficients.

I am pretty new to this area. please bear with me if my questions are a bit dumb.

Thank you.

I am trying to fit a predictive gene-based model in survival analysis. My question is:

can I use LASSO as a variable selection method, and then run a multivariate cox regression to get the coefficients of those variables (genes) instead of using the coefficients from LASSO?

In that case (if I run a multivariate cox regression), I can get p-values, and make an inference for the coefficients.

I am pretty new to this area. Please bear with me if my questions are a bit dumb.

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Jenny
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LASSO - variable selection

I am trying to find a predictive gene-based model in survival analysis.

My question is

can I use LASSO as a variable selection method, and then run a multivariate cox regression to get the coefficients of those variables (genes) instead of using the coefficients from LASSO?

In that case (if I run a multivariate cox regression), I can get p values, and make an inference for the coefficients.

I am pretty new to this area. please bear with me if my questions are a bit dumb.

Thank you.