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when toggle format what by license comment
Jun 1, 2018 at 7:30 history tweeted twitter.com/StackStats/status/1002452351251288064
May 31, 2018 at 15:35 answer added half-pass timeline score: 2
May 24, 2018 at 5:55 comment added Giuseppe Biondi-Zoccai Yes, do it both ways. But probably for prediction purposes the two-step strategy (with separate derivation and validation) is more meaningful. However, your sample might be not large enough for precise modeling. Check for instance this: springer.com/us/book/9780387772431
May 23, 2018 at 18:28 comment added dfife Thanks for the comment. This is a prediction, not an intervention study. The selection criteria and procedures are the same. I suppose we can analyze it both ways and (hopefully) the results show it doesn't matter.
May 23, 2018 at 13:10 comment added Giuseppe Biondi-Zoccai The correct answer depends on the type of study you are conducting (eg intervention vs prediction). In addition, you should be wary of any scenario in which the all-in and the 2-step analyses are conflicting. My recommendation would be in any case, if the selection criteria and procedures are the same, to use a single analysis approach. Conversely, if there are even minor differences in selection or you aim for prediction, go first for a 2-step approach (but with individual patient-level meta-analysis).
May 22, 2018 at 16:48 history asked dfife CC BY-SA 4.0