(edit: below this line I provide additional information in order to address considerations raised in the answer of @Ben which might be relevant to future discussants too)
"[...] Since you don't specify your sampling frame in the question, it is a bit hard to tell what exactly these data represent"
The data are a collection of (quarterly) time series documenting the absolute numbers of population, labour force, employed, unemployed and inactives for (eight) categories of educational attainment, (thirteen) districts and (six) 5-year age slots from 15-65+.
They are contained in three tables with eight, thirteen and six rows respectively and five columns each (per quarter).
In all cases, total population is decomposed into disjoint subsets of sums of individuals (eg persons with post-graduate qualification in total population or persons from District A in inactives, or unemployed aged 20-24 years old, respectively).
"[...]Since you have the counts inside the 2×2 contingency table, and not just their marginal totals, you already have a perfectly good basis for estimating the joint and conditional probabilities for the covariates in your data"
There are no observations for the number of people eg in District A who have finished primary education; that is, the number of people denoted by $x, y, a$ and $b$ in the simplified table I have included in the question, are not given;
the problem I'm facing is how to derive those joint frequencies, denoted in the question as $p_x, p_y, p_a$ and $p_b$.
"[...] If you want to find probabilities of unemployment conditional on these covariates then you will also need some data for employed people with these covariates."
I interpret this as in the following example:
Let UA denote "unemployed in District A" and UB denote "unemployed with a university degree"; also let U denote "Beeing unemployed", A denote "in District A" and B denote "with a university degree".
Then, $Pr(UA \cap UB)=Pr(U|A) \times Pr(A) + Pr(U|B) \times Pr(B)$,
where $Pr(A)$ equals "persons in District A / population" and $Pr(B)$ equals "persons with a university degree / population".
If my interpretation is correct, how should one calculate the conditional probabilities?
My understanding is that my data tables provide figures for the joint distribution of characteristics (eg number of people unemployed AND with a university degree) not conditional distributions.