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Jun 8, 2021 at 10:39 comment added Scortchi @Klik: No - I did have in mind a two-stage nested design, with batch a random effect nested within the fixed effect build; but more because that's a natural way of viewing the results you presented in your question than because it's necessarily a good approach given your goals, constraints, & costs (about which I'd be mostly guessing).
Jun 7, 2021 at 18:58 comment added Klik Thank you for following up with my question - I appreciate the time. I'm glad you pointed out how the sample size scales the results for t-statistics. I had given those scaling terms some attention but wasn't sure what other ways I could approach this. I will follow up by investigating mixed-models - very helpful point. On that note, do you have any favorite mixed-model approaches? I'm implementing this through SQL queries so part of my consideration is ease of implementation.
Jun 7, 2021 at 18:48 vote accept Klik
Jun 7, 2021 at 11:20 history edited Scortchi CC BY-SA 4.0
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Jun 7, 2021 at 10:10 history answered Scortchi CC BY-SA 4.0