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Oct 24, 2022 at 15:18 comment added AdamO @Emos you can't "combine" an OR for two exposures without defining precisely what you mean. Once you do, you should just fit a new univariate model and call it done. You should also get a statistician involved with this project.
Oct 24, 2022 at 12:44 comment added Emos Dear @AdamO,<br/> many thanks for your reply. I am no statistician and I cannot really understand what is happening here. What is W here? And what are X, Y etc? If I do data.frame(table(df$diagnosis, df$PRS_partition1_quantile, df$PRS_partition2_quantile)) I obtain a table like so:> data.frame(t) Var1 Var2 Var3 Freq 1 healthy 1 1 16604 2 disease 1 1 12 ... 49 healthy 5 5 16519 50 disease 5 5 162 Can I then calculate a combined OR for disease, given belonging to class 1..5 of PRS1 and class 1..5 of PRS2? Many thanks in advance
Oct 21, 2022 at 16:18 history answered AdamO CC BY-SA 4.0