Skip to main content
added 81 characters in body; edited tags
Source Link
chl
  • 54.3k
  • 23
  • 227
  • 388

I am trying to understand a GWAS paper which reports the effect of a SNP on outcome as a % variation, e. (egg., 15% variation in xxx levels).

The only information reported are the beta, standard error and p-values. I tried to read the paper but there is no mention of how this is calculated.

The paper in question is hereGenome-wide association meta-analysis for total serum bilirubin levels (Hum. Mol. Genetics, 2009).

Paragraph in question = These SNPs accounts for approximately 17.5, 18.1 and 16.7% of the variation...

If anyone has any clue, please help. I'll be most appreciative.

Thank you,

I am trying to understand a GWAS paper which reports the effect of a SNP on outcome as a % variation. (eg. 15% variation in xxx levels)

The only information reported are the beta, standard error and p-values. I tried to read the paper but there is no mention of how this is calculated.

The paper in question is here

Paragraph in question = These SNPs accounts for approximately 17.5, 18.1 and 16.7% of the variation...

If anyone has any clue, please help. I'll be most appreciative.

Thank you,

I am trying to understand a GWAS paper which reports the effect of a SNP on outcome as a % variation, e.g., 15% variation in xxx levels.

The only information reported are the beta, standard error and p-values. I tried to read the paper but there is no mention of how this is calculated.

The paper in question is Genome-wide association meta-analysis for total serum bilirubin levels (Hum. Mol. Genetics, 2009).

Paragraph in question = These SNPs accounts for approximately 17.5, 18.1 and 16.7% of the variation...

If anyone has any clue, please help. I'll be most appreciative.

Source Link
Sylvia
  • 23
  • 1
  • 4

How to determine % effect on quantitative variable from beta and se values?

I am trying to understand a GWAS paper which reports the effect of a SNP on outcome as a % variation. (eg. 15% variation in xxx levels)

The only information reported are the beta, standard error and p-values. I tried to read the paper but there is no mention of how this is calculated.

The paper in question is here

Paragraph in question = These SNPs accounts for approximately 17.5, 18.1 and 16.7% of the variation...

If anyone has any clue, please help. I'll be most appreciative.

Thank you,