First off, I have read a plethora of answers on this site but can't seem to find something that satisfies my situation below:
library(lme4)
> dput(test2)
structure(list(Subject = structure(c(1L, 1L, 1L, 1L, 1L, 1L,
1L, 1L, 1L, 2L, 2L, 2L, 2L, 2L, 2L, 2L, 2L, 2L, 3L, 3L, 3L, 3L,
3L, 3L, 3L, 3L, 3L, 4L, 4L, 4L, 4L, 4L, 4L, 4L, 4L, 5L, 5L, 5L,
5L, 5L, 5L, 5L, 5L, 5L, 6L, 6L, 6L, 6L, 6L, 6L, 7L, 7L, 7L, 7L,
7L, 7L, 8L, 8L, 8L, 8L, 8L, 8L, 8L, 8L, 8L, 9L, 9L, 9L, 9L, 9L,
9L, 9L, 9L, 9L, 10L, 10L, 10L, 10L, 10L, 10L, 10L, 10L, 10L,
11L, 11L, 11L, 11L, 11L, 11L, 11L, 11L, 11L, 12L, 12L, 12L, 12L,
12L, 12L, 12L, 12L, 12L, 13L, 13L, 13L, 13L, 13L, 13L, 13L, 13L,
13L, 14L, 14L, 14L, 14L, 14L, 14L, 14L, 14L, 15L, 15L, 15L, 15L,
15L, 15L, 16L, 16L, 16L, 16L, 16L, 16L, 16L, 16L, 16L, 17L, 17L,
17L, 17L, 17L, 17L, 17L, 18L, 18L, 18L, 18L, 18L, 18L, 18L, 18L,
18L, 19L, 19L, 19L, 19L, 19L, 19L, 19L, 19L, 19L, 20L, 20L, 20L,
20L, 20L, 20L, 20L, 20L, 20L, 21L, 21L, 21L, 21L, 21L, 21L, 21L,
21L, 21L, 22L, 22L, 22L, 22L, 22L, 22L, 22L, 22L, 22L, 23L, 23L,
23L, 23L, 23L, 23L, 23L, 23L, 23L), .Label = c("153", "204",
"212", "790", "1422", "1427", "1430", "1507", "1508", "1511",
"1512", "1602", "1609", "1618", "5327", "5466", "5753", "5935",
"6424", "7004", "8339", "10806", "12802"), class = "factor"),
Status = structure(c(1L, 1L, 1L, 1L, 1L, 1L, 1L, 1L, 1L,
2L, 2L, 2L, 2L, 2L, 2L, 2L, 2L, 2L, 1L, 1L, 1L, 1L, 1L, 1L,
1L, 1L, 1L, 2L, 2L, 2L, 2L, 2L, 2L, 2L, 2L, 1L, 1L, 1L, 1L,
1L, 1L, 1L, 1L, 1L, 1L, 1L, 1L, 1L, 1L, 1L, 2L, 2L, 2L, 2L,
2L, 2L, 1L, 1L, 1L, 1L, 1L, 1L, 1L, 1L, 1L, 1L, 1L, 1L, 1L,
1L, 1L, 1L, 1L, 1L, 2L, 2L, 2L, 2L, 2L, 2L, 2L, 2L, 2L, 2L,
2L, 2L, 2L, 2L, 2L, 2L, 2L, 2L, 1L, 1L, 1L, 1L, 1L, 1L, 1L,
1L, 1L, 1L, 1L, 1L, 1L, 1L, 1L, 1L, 1L, 1L, 1L, 1L, 1L, 1L,
1L, 1L, 1L, 1L, 2L, 2L, 2L, 2L, 2L, 2L, 3L, 3L, 3L, 3L, 3L,
3L, 3L, 3L, 3L, 2L, 2L, 2L, 2L, 2L, 2L, 2L, 3L, 3L, 3L, 3L,
3L, 3L, 3L, 3L, 3L, 3L, 3L, 3L, 3L, 3L, 3L, 3L, 3L, 3L, 3L,
3L, 3L, 3L, 3L, 3L, 3L, 3L, 3L, 3L, 3L, 3L, 3L, 3L, 3L, 3L,
3L, 3L, 3L, 3L, 3L, 3L, 3L, 3L, 3L, 3L, 3L, 3L, 3L, 3L, 3L,
3L, 3L, 3L, 3L, 3L), .Label = c("Con", "Sub", "Cl"), class = "factor"),
Stim = structure(c(1L, 1L, 1L, 2L, 2L, 2L, 3L, 3L, 3L, 1L,
1L, 1L, 2L, 2L, 2L, 3L, 3L, 3L, 1L, 1L, 1L, 2L, 2L, 2L, 3L,
3L, 3L, 1L, 1L, 2L, 2L, 2L, 3L, 3L, 3L, 1L, 1L, 1L, 2L, 2L,
2L, 3L, 3L, 3L, 2L, 2L, 2L, 3L, 3L, 3L, 1L, 1L, 1L, 2L, 2L,
2L, 1L, 1L, 1L, 2L, 2L, 2L, 3L, 3L, 3L, 1L, 1L, 1L, 2L, 2L,
2L, 3L, 3L, 3L, 1L, 1L, 1L, 2L, 2L, 2L, 3L, 3L, 3L, 1L, 1L,
1L, 2L, 2L, 2L, 3L, 3L, 3L, 1L, 1L, 1L, 2L, 2L, 2L, 3L, 3L,
3L, 1L, 1L, 1L, 2L, 2L, 2L, 3L, 3L, 3L, 1L, 1L, 2L, 2L, 2L,
3L, 3L, 3L, 2L, 2L, 2L, 3L, 3L, 3L, 1L, 1L, 1L, 2L, 2L, 2L,
3L, 3L, 3L, 1L, 2L, 2L, 2L, 3L, 3L, 3L, 1L, 1L, 1L, 2L, 2L,
2L, 3L, 3L, 3L, 1L, 1L, 1L, 2L, 2L, 2L, 3L, 3L, 3L, 1L, 1L,
1L, 2L, 2L, 2L, 3L, 3L, 3L, 1L, 1L, 1L, 2L, 2L, 2L, 3L, 3L,
3L, 1L, 1L, 1L, 2L, 2L, 2L, 3L, 3L, 3L, 1L, 1L, 1L, 2L, 2L,
2L, 3L, 3L, 3L), .Label = c("B", "C", "D"), class = "factor"),
Treatment = structure(c(3L, 2L, 1L, 3L, 2L, 1L, 3L, 2L, 1L,
3L, 2L, 1L, 3L, 2L, 1L, 3L, 2L, 1L, 3L, 2L, 1L, 3L, 2L, 1L,
3L, 2L, 1L, 3L, 2L, 3L, 2L, 1L, 3L, 2L, 1L, 3L, 2L, 1L, 3L,
2L, 1L, 3L, 2L, 1L, 3L, 2L, 1L, 3L, 2L, 1L, 3L, 2L, 1L, 3L,
2L, 1L, 3L, 2L, 1L, 3L, 2L, 1L, 3L, 2L, 1L, 3L, 2L, 1L, 3L,
2L, 1L, 3L, 2L, 1L, 3L, 2L, 1L, 3L, 2L, 1L, 3L, 2L, 1L, 3L,
2L, 1L, 3L, 2L, 1L, 3L, 2L, 1L, 3L, 2L, 1L, 3L, 2L, 1L, 3L,
2L, 1L, 3L, 2L, 1L, 3L, 2L, 1L, 3L, 2L, 1L, 3L, 2L, 3L, 2L,
1L, 3L, 2L, 1L, 3L, 2L, 1L, 3L, 2L, 1L, 3L, 2L, 1L, 3L, 2L,
1L, 3L, 2L, 1L, 3L, 3L, 2L, 1L, 3L, 2L, 1L, 3L, 2L, 1L, 3L,
2L, 1L, 3L, 2L, 1L, 3L, 2L, 1L, 3L, 2L, 1L, 3L, 2L, 1L, 3L,
2L, 1L, 3L, 2L, 1L, 3L, 2L, 1L, 3L, 2L, 1L, 3L, 2L, 1L, 3L,
2L, 1L, 3L, 2L, 1L, 3L, 2L, 1L, 3L, 2L, 1L, 3L, 2L, 1L, 3L,
2L, 1L, 3L, 2L, 1L), .Label = c("None", "V2", "V1"), class = "factor"),
value = c(2.056, 5.819, 5.371, 15.264, 8.942, 7.934, 9.616,
7.752, 6.362, 1.416, 4.82, 5.394, 6.053, 3.23, 3.866, 1.334,
1.152, 1.152, 2.165, 2.267, 2.662, 6.26, 3.153, 5.022, 2.455,
1.023, 1.239, 4.024, 7.428, 41.86, 9.878, 9.313, 10.056,
4.729, 4.776, 1.514, 3.085, 3.845, 5.605, 5.411, 4.991, 1.771,
1.418, 2.934, 19.516, 11.404, 11.081, 30.123, 13.1, 13.57,
1.612, 0.903, 1.622, 3.293, 1.23, 1.277, 2.185, 4.405, 5.247,
22.581, 8.429, 7.529, 7.651, 6.508, 8.511, 1.427, 1.719,
1.884, 1.502, 1.436, 2.026, 0.376, 0.631, 0.284, 2.653, 2.307,
1.416, 15.086, 5.152, 2.666, 10.176, 3.574, 3.349, 6.896,
4.051, 5.826, 14.228, 6.891, 5.277, 10.309, 4.732, 7.404,
2.054, 2.602, 1.856, 8.099, 4.793, 5.258, 1.948, 2.016, 1.72,
3.523, 5.142, 5.03, 17.116, 7.487, 7.235, 8.407, 3.585, 3.04,
4.506, 4.026, 10.015, 3.807, 8.342, 4.873, 4.21, 5.79, 20.031,
3.12, 4.239, 42.889, 18.702, 19.384, 19.981, 23.454, 18.292,
62.969, 19.677, 25.142, 55.025, 30.228, 20.731, 18.017, 22.562,
8.579, 8.663, 17.277, 7.495, 7.351, 38.814, 24.896, 30.968,
39.639, 39.108, 18.909, 65.557, 56.319, 32.419, 7.28, 2.734,
1.494, 5.23, 4.252, 1.923, 9.488, 2.662, 1.644, 6.813, 8.478,
6.799, 33.731, 13.292, 10.854, 12.287, 3.597, 4.815, 33.283,
7.684, 8.271, 37.239, 9.026, 9.107, 38.36, 28.966, 32.334,
2.691, 2.737, 2.949, 3.163, 4.345, 5.337, 5.419, 9.01, 8.911,
1.155, 0.485, 0.863, 5.354, 0.697, 1.304, 4.537, 2.098, 1.517
)), row.names = c(4L, 5L, 6L, 7L, 8L, 9L, 10L, 11L, 12L,
16L, 17L, 18L, 19L, 20L, 21L, 22L, 23L, 24L, 28L, 29L, 30L, 31L,
32L, 33L, 34L, 35L, 36L, 40L, 41L, 42L, 43L, 44L, 45L, 46L, 47L,
51L, 52L, 53L, 54L, 55L, 56L, 57L, 58L, 59L, 66L, 67L, 68L, 69L,
70L, 71L, 75L, 76L, 77L, 78L, 79L, 80L, 87L, 88L, 89L, 90L, 91L,
92L, 93L, 94L, 95L, 99L, 100L, 101L, 102L, 103L, 104L, 105L,
106L, 107L, 111L, 112L, 113L, 114L, 115L, 116L, 117L, 118L, 119L,
123L, 124L, 125L, 126L, 127L, 128L, 129L, 130L, 131L, 135L, 136L,
137L, 138L, 139L, 140L, 141L, 142L, 143L, 147L, 148L, 149L, 150L,
151L, 152L, 153L, 154L, 155L, 159L, 160L, 162L, 163L, 164L, 165L,
166L, 167L, 174L, 175L, 176L, 177L, 178L, 179L, 183L, 184L, 185L,
186L, 187L, 188L, 189L, 190L, 191L, 195L, 198L, 199L, 200L, 201L,
202L, 203L, 207L, 208L, 209L, 210L, 211L, 212L, 213L, 214L, 215L,
219L, 220L, 221L, 222L, 223L, 224L, 225L, 226L, 227L, 231L, 232L,
233L, 234L, 235L, 236L, 237L, 238L, 239L, 243L, 244L, 245L, 246L,
247L, 248L, 249L, 250L, 251L, 255L, 256L, 257L, 258L, 259L, 260L,
261L, 262L, 263L, 267L, 268L, 269L, 270L, 271L, 272L, 273L, 274L,
275L), class = "data.frame")
Model:
mod.lmer <- lmer(value ~ Status + Treatment + Stim + Treatment*Status*Stim + (1|Subject),
data = test2)
Notably, the following things do not produce similar results:
- anova() type 3 and Anova() type 3
- summary() and anova() type 3
I have tried options(contrasts = c("contr.sum", "contr.poly"))
and it does not change any results. I have run my pre-determined contrasts of interest using emmeans, which had high significance, so I'm having a hard time understanding why the Anova() type 3 and summary() aren't showing any significance/similar results. I was initially going to use type 3 Anova for my data due to the contrasts I'm interested in and mildly unbalanced data, but now I'm not sure which anova to use for my report.
> anova(mod.lmer, type = 1)
Type I Analysis of Variance Table with Satterthwaite's method
Sum Sq Mean Sq NumDF DenDF F value Pr(>F)
Status 213.07 106.53 2 19.999 2.7098 0.0909098 .
Treatment 1796.00 898.00 2 147.061 22.8417 2.298e-09 ***
Stim 622.26 311.13 2 147.647 7.9139 0.0005433 ***
Status:Treatment 549.26 137.32 4 147.067 3.4928 0.0093286 **
Treatment:Stim 584.18 146.04 4 147.072 3.7148 0.0065363 **
Status:Stim 385.45 96.36 4 147.755 2.4511 0.0486018 *
Status:Treatment:Stim 59.95 7.49 8 147.088 0.1906 0.9918876
---
Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1
> anova(mod.lmer, type = 3)
Type III Analysis of Variance Table with Satterthwaite's method
Sum Sq Mean Sq NumDF DenDF F value Pr(>F)
Status 217.10 108.55 2 20.041 2.7611 0.087273 .
Treatment 1837.07 918.53 2 147.097 23.3640 1.543e-09 ***
Stim 523.71 261.86 2 147.852 6.6606 0.001699 **
Status:Treatment 564.47 141.12 4 147.093 3.5895 0.007990 **
Treatment:Stim 624.52 156.13 4 147.093 3.9713 0.004331 **
Status:Stim 387.16 96.79 4 147.777 2.4620 0.047779 *
Status:Treatment:Stim 59.95 7.49 8 147.088 0.1906 0.991888
---
Signif. codes: 0 ‘***’ 0.001 ‘**’ 0.01 ‘*’ 0.05 ‘.’ 0.1 ‘ ’ 1
> Anova(mod.lmer, type = 3)
Analysis of Deviance Table (Type III Wald chisquare tests)
Response: value
Chisq Df Pr(>Chisq)
(Intercept) 1.7023 1 0.1920
Status 0.8426 2 0.6562
Treatment 0.2184 2 0.8966
Stim 0.4451 2 0.8005
Status:Treatment 3.2780 4 0.5124
Treatment:Stim 3.2279 4 0.5204
Status:Stim 2.6306 4 0.6214
Status:Treatment:Stim 1.5248 8 0.9923
Summary:
> summary(mod.lmer)
Linear mixed model fit by REML. t-tests use Satterthwaite's method ['lmerModLmerTest']
Formula: value ~ Status + Treatment + Stim + Treatment * Status * Stim + (1 | Subject)
Data: test2
REML criterion at convergence: 1196.2
Scaled residuals:
Min 1Q Median 3Q Max
-2.0551 -0.3745 0.0005 0.2780 3.6174
Random effects:
Groups Name Variance Std.Dev.
Subject (Intercept) 74.54 8.634
Residual 39.31 6.270
Number of obs: 194, groups: Subject, 23
Fixed effects:
Estimate Std. Error df t value Pr(>|t|)
(Intercept) 4.89297 3.75025 48.48368 1.305 0.198
StatusSub 2.39119 5.92696 56.30030 0.403 0.688
StatusCl 5.05503 5.50718 43.78039 0.918 0.364
TreatmentV2 -0.15767 3.25774 147.17807 -0.048 0.961
TreatmentV1 -1.36205 3.25774 147.17807 -0.418 0.676
StimC 1.70903 3.18599 147.39224 0.536 0.592
StimD -0.06519 3.18599 147.39224 -0.020 0.984
StatusSub:TreatmentV2 -0.81671 5.34245 147.25141 -0.153 0.879
StatusCl:TreatmentV2 0.27653 4.67391 147.10108 0.059 0.953
StatusSub:TreatmentV1 1.22546 5.23640 147.42567 0.234 0.815
StatusCl:TreatmentV1 7.13076 4.67391 147.10108 1.526 0.129
TreatmentV2:StimC -0.34855 4.39879 147.11046 -0.079 0.937
TreatmentV1:StimC 6.53316 4.39879 147.11046 1.485 0.140
TreatmentV2:StimD -0.19866 4.39879 147.11046 -0.045 0.964
TreatmentV1:StimD 4.00316 4.39879 147.11046 0.910 0.364
StatusSub:StimC -3.95019 5.11692 147.69916 -0.772 0.441
StatusCl:StimC -1.28903 4.62419 147.20128 -0.279 0.781
StatusSub:StimD -0.97558 5.24777 148.10277 -0.186 0.853
StatusCl:StimD 4.74162 4.62419 147.20128 1.025 0.307
StatusSub:TreatmentV2:StimC 1.71993 6.96497 147.15964 0.247 0.805
StatusCl:TreatmentV2:StimC 2.77555 6.46642 147.06631 0.429 0.668
StatusSub:TreatmentV1:StimC 6.14800 6.88397 147.25849 0.893 0.373
StatusCl:TreatmentV1:StimC 4.09084 6.46642 147.06631 0.633 0.528
StatusSub:TreatmentV2:StimD 0.66771 7.09809 147.15476 0.094 0.925
StatusCl:TreatmentV2:StimD 4.43823 6.46642 147.06631 0.686 0.494
StatusSub:TreatmentV1:StimD 4.23759 7.01862 147.24976 0.604 0.547
StatusCl:TreatmentV1:StimD 2.84270 6.46642 147.06631 0.440 0.661
Correlation matrix not shown by default, as p = 27 > 12.
Use print(x, correlation=TRUE) or
vcov(x) if you need it