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I'm trying to get my head around running more complex mixed models in R (only previously run time-series repeated measures). I have some data from a study where participants completed a series of exercise bouts at two different intensities under two different conditions. Order for condition was randomised, but within each condition the order for intensity was the same — 6 bouts alternating between low and high intensity. The below diagram illustrates the data nesting. I'm not quite sure what the term is for the type of relationship between intensity and bout, is this a partially crossed/nested?

enter image description here

An example of the current data structure for a participant is below.

pid condition intensity bout outcome1 outcome2 ...
01 control low 1
01 control low 3
01 control low 5
01 control high 2
01 control high 4
01 control high 6
01 experimental low 1
01 experimental low 3
01 experimental low 5
01 experimental high 2
01 experimental high 4
01 experimental high 6

Initially I analysed this with a repeated measures ANOVA with bout coded as 1, 2, 3 for the first, second and third bouts within each intensity. However, I know there is a main effect of bout and a bout*intensity interaction for several outcome variables, hence I don't think this approach is optimal.

Using R and lme4, how would I structure the formula to model the relationship between bout and intensity to best reflect how the participants actually completed the exercise session? For now I've only run the model including the factors as fixed effects and participant ID as the grouping variable. Ultimately, I want to know whether an outcome variable (e.g., outcome1) changes across bouts, both within each intensity and within each condition.

library(lme4)

model1 <- lmer(outcome1 ~ condition * intensity * bout + (1 | pid), data = data)
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  • $\begingroup$ How is bout encoded in R? Is it numeric or a factor? $\endgroup$
    – Roland
    Commented Oct 10 at 6:26

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