There is not enough information provided to establish the exact meaning of the word "trend." For example, two normal random variates were generated and seem to overlap as below.
Not knowing any better we do a two tailed t-test to see how they differ and get $p=0.495,$ not significant. Next, we examine if there is any trend or structure for the difference between them by using a pair-wise t-test and get $p=0$.
This is because we didn't ask how the data was generated. In this case, the pair-wise correlation between Sample A and Sample B is 1, and for each pair Sample B = Sample A + 0.1. That is, if the samples are not independent, and are correlated, we have to account for that in choosing our statistical testing.
Thus, I would ask what "trend" means by asking "What do you mean by trend?" In general, a "trend" can be very predictive, or not at all predictive depending on the circumstances.