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Cox proportional hazards regression is a semi-parametric method for survival analysis. No distributional form needs to be assumed, only that the effect of one-unit increase in a covariate is a constant multiple.
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Problem with Cox regression
Using drug dispensing data, I am trying to examine the association between proportion of days covered (PDC) by a drug and disease relapse. PDC is calculated by drug's supply divided by follow-up time. …
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Is it appropriate to use Cox regression when risk of event is higher at the start of study?
as per title, like to check if it is appropriate to use Cox regression when the risk of event appears to decrease with follow-up time?
If it is not appropriate, what model should I be using instead? …