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Group differences broadly refer to statistics which quantify the differences between two or more subpopulations.

2 votes
1 answer
635 views

Overview of concepts of the methods that this Single-Cell Differential Expression (SCDE) too...

I'm unsure about how this tool works, but as I understand it, it tries to use Bayesian probability in order to differentiate the two different groups from each other as well as some other methods. Ri …
CinchBlue's user avatar
  • 163
4 votes
1 answer
262 views

What is the relationship between differential analysis and hierarchial clustering?

I'm currently in an internship for R bioinformatics, where I'm writing software for single-cell RNA sequencing analysis. We're looking for differentially expressed genes between groups, but I don't un …
CinchBlue's user avatar
  • 163