are these estimators unbiased?
Quite evidently, they are not. In fact, you can easily choose an underlying distribution $F$ of $X$ such that $E[z_3] \neq \zeta_3$ and/or $E[z_4] \neq \zeta_4$ when the sample size $n$ is finite.
For example, fix $n = 2$, let $X$ be a discrete random variable following the probability mass function $P(X = -1) = 0.4$, $P(X = 1/2) = 0.4$, $P(X = 1) = 0.2$. Let $X_1, X_2 \text{ i.i.d.} \sim X$, it then follows that
\begin{align*}
z_3 = 0, \quad z_4 = 1.
\end{align*}
On the other hand, since
\begin{align*}
& \mu = E[X] = -0.4 + 0.2 + 0.2 = 0, \\
& \sigma^2 = E[X^2] = 0.4 + 0.1 + 0.2 = 0.7, \\
& \mu_3 = E[X^3] = -0.4 + 0.05 + 0.2 = -0.15, \\
& \mu_4 = E[X^4] = 0.4 + 0.025 + 0.2 = 0.625,
\end{align*}
we have
\begin{align*}
& \zeta_3 = \frac{\mu_3}{\sigma^{3/2}} = \frac{-0.15}{0.586} = -0.256, \\
& \zeta_4 = \frac{\mu_4}{\sigma^{2}} = \frac{0.625}{0.49} = 1.276, \\
\end{align*}
Therefore, $E[z_3] \neq \zeta_3$, $E[z_4] \neq \zeta_4$.
By this example, it can be seen that replacing the denominator in the definition of $z_3$ and $z_4$ with the bias-corrected standard deviation wouldn't help either.
One thing to note though, for any $F$, provided that $X_1, \ldots, X_n$ are i.i.d. draws from $F$, it can be shown that $z_3$ and $z_4$ converges to $\zeta_3$ and $\zeta_4$ with probability 1 as $n \to \infty$. This is just an easy application of SLLN: for example, by SLLN,
\begin{align*}
& \frac{1}{n}\sum_{i = 1}^n(X_i - \bar{X})^3 \\
=& \frac{1}{n}\sum_{i = 1}^n (X_i - \mu)^3 - \frac{3}{n}\sum_{i = 1}^n(X_i - \mu)^2(\mu - \bar{X}) \\
& + \frac{3}{n}\sum_{i = 1}^n(X_i - \mu)(\mu - \bar{X})^2 +
(\mu - \bar{X})^3 \\
\to & E[(X - \mu)^3] \quad\text{ with probability 1},
\end{align*}
whence $z_3 \to \zeta_3$ with probability $1$. Similarly, one can show that $z_4 \to \zeta_4$ with probability $1$. One caveat is, this result is not equivalent to $E[z_k] \to \zeta_k$, $k = 3, 4$, because almost surely convergence does not guarantee convergence by moments. That is, we still cannot claim $z_k$ are asymptotically unbiased unless we impose more conditions such as uniform integrability.
In summary, we can say that $z_k$ are consistent estimators of $\zeta_k$, but in general they are not unbiased, or even asymptotically unbiased estimators of $\zeta_k$.