I am working on time series prediction. I have two data sets $D1=\{x_1, x_2,....x_n\}$ and $D2=\{x_n+1, x_n+2, x_n+3,...., x_n+k\}$. I have three prediction models: $M1, M2, M3$. All of those model are trained using samples in data set $D1$, and their performance is measured using the samples in data set $D2$. Let say the performance metrics is MSE (or anything else). The MSE of those models when measured for data set $D2$ are $MSE_1, MSE_2, $ and $MSE_3$. How can I test that improvement of one model over another is statistically significant.
For example, let say $MSE_1=200$, $MSE_2=205$, $MSE_3=210$, and total number of sample in data set $D2$ based upon which those MSE are calculated is 2000. How can I test that $MSE_1$, $MSE_2$, and $MSE_3$ are significantly different. I would greatly appreciate if anyone can help me in this problem.