MY PROBLEM: I need to test for statistical significance between the three groups. The problem comes when extremely large numbers are involved and the chi-square test is always significant. I read several related questions however I didn't find a solution. What test should I use?

1. How to test for a statistically significant difference between 3 percentages?
2. Which statistical test for statistical significance of positive result in 5 categories of samples
3. How to test for a statistically significant difference between multiple unbalanced groups

MY DATA: We classify tweets into three different groups if the account is: bot/non-bot/self-declared. Then each of the tweets is classified into 18 different topics. We need to check if there are topics where tweets sent by accounts classified as bots (or non-bots or self-declared) are more common.

The total number of tweets written from each of the groups is:

• Bot 1,106,255
• Non-Bot 8,218,070
• Self Declared 1,101,219

For Topic 14 and Topic 9 the distribution is as follows:

Following this method, we plotted this chart :