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In biostatistics, fixed-effects may mean population-average effects. In econometrics, fixed-effects may represent the observed quantities in terms of explanatory variables that are treated as if the quantities were non-random.
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votes
Why Generalized estimating equation (GEE) is not popular?
I don't think the reason for GEE not to be popular is "software availability/implementation". Almost all software I am aware of and have been working for a while (STATA, R, SPSS) can do GEE. I wonder …