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Cox proportional hazards regression is a semi-parametric method for survival analysis. No distributional form needs to be assumed, only that the effect of one-unit increase in a covariate is a constant multiple.

2 votes
2 answers
2k views

Age as a time-dependent covariate

I have some confusion around time-dependent covariates / coefficients. I'm trying to run a cox regression with age as a time-dependent covariate. Lets say the variable is age-at-first-drivers-license …
shrub's user avatar
  • 113
0 votes
1 answer
191 views

Survival Analysis - 30% right censored data

Just looking for some clarity regarding time-to-event (death) data when there is a large proportion of right censored data (lots of survival). Is this a serious problem for a proportional hazards mode …
shrub's user avatar
  • 113
0 votes
0 answers
106 views

Interpreting a hazard ratio for time-dependent coefficients

I have a cox model with two main effects (x,y) and two interaction terms (xt, yt) where t is time. I am having some trouble interpreting the hazard ratios. Does the hazard ration become more of an ins …
shrub's user avatar
  • 113
1 vote
0 answers
131 views

Test assumption of common baseline - Adersen-Gill Cox regression?

I'm running a Andersen-Gill recurrent (multiple events) cox model and I want to test the assumption of common baseline across events. Is this as simple as entering 'event' into the model and checking …
shrub's user avatar
  • 113
1 vote
2 answers
5k views

Interpreting hazard ratios in stratified models

I am unsure how to interpret hazard ratios from cox-proportional hazard models that include 1 or more stratified terms. For example, say I run a cox regression with treatment as a covariate and stra …
shrub's user avatar
  • 113