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Statistical significance is a characteristic of a statistic viewed in light of a null hypothesis and a given significance level. It reflects whether the statistic belongs to the rejection region (is statistically significant) or the acceptance region (is not statistically significant).

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What is a good measure (or set of measures) for the difference between two sample sets?

The general approach is to model your latencies in each condition with some distribution, like a Gaussian, and test whether the means of those two distributions are different, e.g. using a t-test. Thi …
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