An estimator is efficient if it reaches the Cramér-Rao Lower Bound and since it is efficient, it is also the UMVU estimator of the parametric function $\tau(\theta)$. But Cramér-Rao inequality and the related lower bound hold if and only if two assumptions are satisfied: 1) the support of $X's$ does not depend on $\theta$ and 2) the first derivative wrt to $\theta$ and the intgral wrt to $\mathbf{x}$ are interchangeable.
If we are in a case in which, instead, the support of the $X's$ depends on $\theta$, e.g. if $f(x;\theta)\sim U(0,\theta)$, can we state that an efficient estimator does not exist since the Cramér-Rao inequality does not hold? Or there are some other ways to find an efficient estimator?