# How to perform a meta-analysis on change from baseline after a treatment?

I am trying to run a meta-analysis calculating the mean effect size of a manual therapy treatment on pressure pain threshold pre-post treatment (i.e. within-group change), so there is no comparison to sham/control. I will be using mean change from baseline (continuous) and I have SDs/CIs of the change. There are 10 studies, and most studies have multiple testing sites (e.g. at the lower back and at the calf) so each site needs to be included separately. I’ll need to run it under a random-effects model. Can I do this? And if so, how do I go about it?

Most information out there about meta-analysis is very focused on inter-group comparisons so I've been unable to find a clear answer.