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Data mining uses methods from artificial intelligence in a database context to discover previously unknown patterns. As such, the methods are usually unsupervised. It is closely related but not identical to machine learning. Key tasks of data-mining are cluster analysis, outlier detection and mining of association rules.
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What to do with a small (27) medical dataset?
I agree with JMS, you will need to plot each of your variable first because PCA requires the normality assumption. If your variables are not normally distributed then it is not appropriate to use PCA …