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Results tagged with meta-analysis
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user 73691
Methods focused on contrasting and combining results from different studies, in the hope of increasing precision and external validity.
8
votes
1
answer
9k
views
Meta-analysis of trials given hazard ratios
I'm trying to do a meta-analysis in R (using metafor) of trials where the outcomes are hazard ratios and I'm given the 95% CI for them and/or the standard error and n.
So if I have columns like:
Tri …
- 473
4
votes
1
answer
617
views
Testing for interaction between subgroups across multiple trials - meta-analytical test for ...
I've got 3 trials, A, B, C.
These test drug X vs placebo, giving an HR for benefit of survival vs. placebo.
There is a dichotomous subgroup analysis, for clarity let's say patients > 50 years old, a …
- 473
3
votes
1
answer
172
views
Meta-regression with highly-correlated predictors? Should I do 2 analyses? Example in R
I'm trying to do meta-regression with a lot of trials (>40 trials with >100 'arms') investigating the efficacy of a procedure (abl) and any 'addon' procedure. Each trial will have 2 or more arms. In s …
- 473
2
votes
2
answers
229
views
Meta-regression / multivariate analysis of trials with a binary outcme
I have a series of single-armed trials where the outcome is a binary response. Imagine a trial where you have no control arm; you merely give 100 patients a procedure (which can be done in many differ …
- 473