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I'm trying to understand using Welch's t-statistic. I'd like to compute the t-score between two distributions with different numbers of samples and different variances. The Null hypothesis is that both means are equal.

Looking at the Wikipedia entry, it gives the computation for the t-score and the degrees of freedom, but not much else.

I've seen tables (linked to from here) of t-score vs. degrees of freedom (for Welch's test), but it is unclear how the degrees of freedom is used. For the typical Student's t-score (equal variance and sample size), (presuming I have enough samples in the group), I simply integrate the area under the normal distribution for all values greater than $|t \cdot \sigma|$. I use this sum to get a p-value.

Question:

How is the degrees of freedom used to compute the statistical significance of the rejection of the Null hypothesis (i.e. p-value)?

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    $\begingroup$ 1. There's no good reason to use a normal approximation to the distribution of a t-statistic. Why would you not integrate the t pdf (at the right number of d.f.) instead? Effectively exact answers are no harder than approximate ones. 2. The Welch t-distribution and df are only approximate but if you can integrate the t there's no great difficulty in doing it for this case. (though in practice you can just call library functions anyway, people have already done the hard work of designing, writing and testing efficient calculations). $\endgroup$
    – Glen_b
    Commented Mar 24, 2019 at 8:00

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The degrees of freedom $\nu$ in a Welch 2-sample t test depends on sample sizes $n_1$ and $n_2$ and sample variances $S_1^2$ and $S_2^2,$ as shown in your Wikipedia link.

The number $\nu$ of degrees of freedom for a Welch test satisfies $$\min(n_1 - 1, n_2 - 1) \le \nu \le n_1 + n_2 - 2.$$ Roughly speaking, $\nu$ is near its upper bound when the ratio $S_1^2/S_2^2$ is near $1$ and near its lower bound when this ratio is far from $1.$ [Note that $\nu = n_1 + n_2 - 2$ in the pooled two-sample t test where one assumes that $\sigma_1^2 = \sigma_2^2$ and hence the sample variances tend to be nearly equal.]

Once you have the value of $\nu,$ then the P-value associated with the Welch t statistic is found in the same way as it is in the pooled t test. The only slight exception might be that many computer implementations of the Welch test allow non-integer values of $\nu,$ which do not occur in the case of the pooled t test.

Here is an example (in R) using relatively small $n_1 = 10$ and $n_2 = 11.$ Population means differ, so that we might hope to reject $H_0: \mu_1 = \mu_2$ against $H_a: \mu_1 \ne \mu_2.$ Also, population variances differ, so that one should use the Welch test instead of the pooled test. However, the power is not large enough to reject $H_0$ so the difference in means goes undetected. Boxplots of the two samples are shown below, followed by output from R for the Welch test.

set.seed(2019)
x1 = rnorm(10, 100, 10);  x2 = rnorm(11, 90, 15)

enter image description here

t.test(x1, x2)

        Welch Two Sample t-test

data:  x1 and x2
t = 1.5964, df = 16.2, p-value = 0.1297
alternative hypothesis: true difference in means is not equal to 0
95 percent confidence interval:
 -3.145136 22.406901
sample estimates:
mean of x mean of y 
 96.88794  87.25706 

Notice that $\min(9, 10) = 9 \le \nu = 16.2 \le 19,$ according to the inequality displayed above. The sample variances are $S_1^2 = 96.85,\, S_2^2 = 293.80,$ so it is not surprising that $\nu < n_1 + n_2 = 19.$

The P-value is the sum of the areas beneath the density curve of Student's t distribution with $\nu = 16.2$ to the left of $-1.5964$ and to the right of $1.5964$ (outside the vertical dotted lines in the figure below). A direct computation in R gives the the same P-value as in the printout above, where it is shown to four decimal places.

2 * pt(-1.5964, 16.2)
[1] 0.1297201

enter image description here

Notes: (1) For the population parameters and sample sizes used to generate the fake data in this example, the power of the Welch test is about 0.4, so it is not surprising we failed to reject. Power is simulated below:

set.seed(323)
p.val = replicate( 10^5, 
        t.test (rnorm(10,100,10), rnorm(11,90,15))$p.value  )
mean(p.val < .05)
[1] 0.39912

(2) An (inappropriate) pooled t test on these data yields $T=1.537,\; \nu = 19,$ and so a P-value about $0.14.$

2 * pt(-1.537, 19)
[1] 0.14078

Formulas for Welch and pooled t statistics differ, giving exactly the same numerical value if $n_1 = n_2.$ So in the 'balanced case', the essential difference between Welch and pooled tests is $\nu.$

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    $\begingroup$ This is not the place for many details about R. However, R codes dt, pt and qt correspond the PDF, CDF, and inverse CDF (quantile) functions of a t distribution. Similarly, dnorm, pnorm, and qnorm are PDF, CDF, and quantile functions of a normal distribution. [Parameters appear as arguments to these functions]. Many useful distributions do not have 'closed-form' formulas for their CDFs. Then numerical integration or approximation methods are req'd. These methods are 'programmed into' major stat and math software packages. Historically, often-used values appeared in printed tables. $\endgroup$
    – BruceET
    Commented Mar 25, 2019 at 1:29

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