Linked Questions

75 votes
33 answers
7k views

What are the worst (commonly adopted) ideas/principles in statistics?

In my statistical teaching, I encounter some stubborn ideas/principles relating to statistics that have become popularised, yet seem to me to be misleading, or in some cases utterly without merit. I ...
9 votes
1 answer
6k views

Difference between Repeated measures ANOVA, ANCOVA and Linear mixed effects model

What is the best way to analyze these data: Subjects are divided in two "Group" (Treatment A and B). "Weight" is recorded before and 3 months after treatment. Outcome variable: ...
rnso's user avatar
  • 10.2k
6 votes
1 answer
3k views

Controlling for baseline in pre-post between design: using $\Delta(T_2-T_1)$ or controlling for T1 in the regression model (or both)? [duplicate]

I have a mixed between-within design, with three groups and Pre (T1) and Post (T2) measurements. I'm hesitating on the right statistical analyses to do, but I would like to compare each group to the ...
rempsyc's user avatar
  • 291
6 votes
1 answer
2k views

How to properly perform "change from baseline" (pre-post) analysis adjusting for pre using lme4 in R?

Let's assume I have the following data set, consisting of pre (t1) and post (t2) measurements. I want to check, if there is a significant effect over time (t1, t2). ...
humbleasker's user avatar
5 votes
2 answers
610 views

How should interactions be modeled in mixed-models?

It is confusing because I get so many different sources claiming different ideas. I am going to try to make it simple. Several individuals organised in 3 groups. We measure multiple variables at two ...
Javier Hernando's user avatar
4 votes
1 answer
3k views

Analysing change scores via linear mixed effects model with baseline adjustment?

I am still trying to find a model for a large dataset, approximately 1-5 measurements per patient (over time), one is the baseline value at t=0. The researcher is interested in the change over time ...
Kathrin's user avatar
  • 195
4 votes
1 answer
1k views

Different ways to include pre-test performance as a covariate in a linear mixed-effect regression. Which is correct?

I have a pre-post experimental design, where I have measured participants' performance in three courses (tasks; A, B, C) at both pre and post-test. The study is a learning experiment. 60 elite alpine ...
Cmagelssen's user avatar
2 votes
1 answer
620 views

Should I include covariates with a non-linear relationship to the dependent variable in linear regression?

In my linear regression model, baseline BMI is a significant predictor of BMI change following a weight loss intervention and including it improves fit (e.g. AIC). But it is strongly associated with ...
Judderman88's user avatar
4 votes
1 answer
295 views

Change Score or Regressor Variable Method - Should I regress $Y_1$ over $X$ and $Y_0$ or $(Y_1-Y_0)$ over $X$

I have data about investment preferences 1 year before the Covid and during the Covid lockdown. Some changes appear using simple T-Test. I want to be able to assess if these changes are particularly ...
L. M. 's user avatar
  • 85
1 vote
0 answers
178 views

Keeping baseline as predictor with change score as outcome in this peculiar scenario

It is generally recommended that baseline should not be kept as predictor if change score ...
rnso's user avatar
  • 10.2k
1 vote
1 answer
115 views

Subgroup analysis: post hoc test interpretation

I am modeling treatment effect in a hypothetical case where only a subset of the sample has disease-related impairment on the outcome of interest. I only expect treatment effects in this subset, but ...
Evan's user avatar
  • 225
3 votes
0 answers
109 views

How is it possible, that statisticians have OPPOSITE view on the analysis of change from baseline adjusted for baseline?

I always thought, that mathematics, thus statistics, are both strict sciences. So, two mathematicians cannot speak about the same topic and have contrary views on it. In the pharmaceutical industry, ...
abrakadabros's user avatar
2 votes
1 answer
59 views

Analysing change data between 3 groups

I have used a mixed-model ANOVA to examine changes in weight following an 8-week intervention in 3 groups (Control, Diet A, & Diet B). The ANOVA identified significant within group differences ...
Exer_Phys's user avatar
2 votes
1 answer
63 views

Is it reasonable/possible to use pre-scores as predictors of change?

In change analyses (of any variable, from pre to post) we usually controll for the pre-score, as it may affect the rate of change. However, what if I am especially interested in the effect of the pre ...
user405152's user avatar
0 votes
1 answer
29 views

Is it appropriate to use GLMM for the dataset I have

I am interested in determining the influence of biotic (initial height) and abiotic (light, canopy, soil moisture content, soil nutrients, rainfall, and temperature) factors in the absolute height-...
Dyanna's user avatar
  • 1