Skip to main content
5 votes

A=B, A=C, B>C: Is this a violation of transitivity in a network meta-analysis?

One way to quantify the departure from transitivity is to add up the A-B, B-C, and C-A differences. Under transitivity, this will have mean zero, and variance equal to the sum of the three variances, ...
Thomas Lumley's user avatar
4 votes
Accepted

Network Meta-Analysis: Single Arm vs Contrasts Strategy Pros and Cons

The idea of how one can use single arm trials is that you assume that outcomes vary across trials, but that they are somewhat similar (assumption of exchangeability). If you have multiple single-arm ...
Björn's user avatar
  • 35.2k
4 votes

Why is there a discrepancy between the underlying meaning of variance between basic statistics and meta-analyses?

What you denote as $v_d$ is not the variance of raw data, but a variance of a derived statistic based on a bunch of raw data. To distinguish the sample variance of raw data from the variance of a ...
Wolfgang's user avatar
  • 17.9k
3 votes
Accepted

Meta-analysis based on cohort studies only

A mixed effects logistic regression (if the outcome is binary/binomial) is certainly one plausible approach that could deal with the situation that all studies were essentially identical, in identical ...
Björn's user avatar
  • 35.2k
3 votes
Accepted

Is there a method/package that combines multivariate and network meta-analysis?

You can conduct network meta-analyses also with metafor. See help(rma.mv) and see these examples: https://wviechtb.github.io/...
Wolfgang's user avatar
  • 17.9k
3 votes

Meta-analysis data from studies comparing the “ecological” effect of a policy when some communities are shared by different studies?

One of the points we like to teach is that you are not required to do a meta-analysis, but if you do, you need to justify undertaking one. In this case, you would have a very tough argument to ...
abousetta's user avatar
  • 1,290
2 votes
Accepted

Learning WinBUGS programming for network meta-analysis

I was in a similar situation like one year ago. And I had to learn NMA models and BUGS at the same time. However, I think better way is starting with pairwise meta-analysis (conventional meta-analysis)...
2 votes

Network Meta-Analysis: Single Arm vs Contrasts Strategy Pros and Cons

I will answer your questions labelled as you have them (a) there is no statistical reason for excluding cohort studies from your analysis but there might be substantive reasons if they are performed ...
mdewey's user avatar
  • 18.4k
2 votes

Network meta-analysis of diagnostic test accuracy studies

How you do your network meta-analysis in R will depend on the nature of your input data, number of competing diagnostic tests being compared in each study, whether or not you have any covariate ...
Isabella Ghement's user avatar
2 votes
Accepted

Network Meta-analysis with poisson regression

Yes, a network meta-analysis is quite general and can be applied to any probability model including Poisson. The underlying assumption is that multiple interventions have been applied to different ...
Geoffrey Johnson's user avatar
2 votes
Accepted

Network meta-analysis of correlation coefficients: a logical paradox?

There are two points to comment on. Note that correlation coefficients do not measure differences, but agreement. It is also right that correlation coefficients per se are not transitive. Of course ...
Gerta Rücker's user avatar
1 vote

Meta-analysis based on cohort studies only

Do you have raw individual data with 0/1 responses in each study? If so, you can use each study as a group indicator in random intercepts and slopes in binary regression with mixed effects. If the ...
DrJerryTAO's user avatar
  • 2,373
1 vote
Accepted

Completely different inferences between single-trial difference and meta-analysis comparison

The model you are using is a random-effects model that allows for heterogeneity. But with two studies included in the analysis (study A is not even included, since it only has a single arm), there is ...
Wolfgang's user avatar
  • 17.9k
1 vote

Network meta analysis without standard deviations

Using the ratio of means implies a very different effect measure than Cohen's D or some other difference in absolute values. That does not necessarily mean it's bad, but simply that you think that e.g....
Björn's user avatar
  • 35.2k
1 vote

Simultaneous network meta-analysis for multiple treatments and outcomes

All the NMAs I have done have been within a Bayesian framework, so I may be wrong here but I believe the frequentist implementations already use a multivariate framework in order to estimate the ...
user177051's user avatar
1 vote

Network-Meta Analysis of Observational Studies

The primary issues are the same as in observational meta-analyses, the exchangeability of subjects within studies between the treatment groups as well as differences between studies in what they ...
hlsmith's user avatar
  • 156
1 vote

Meta-analysis for complex data with many treatments (and often no controls)?

For a start, you ideally need meaningful comparisons of methods within studies. Otherwise, I'm not sure there is much you can do. That's because studies probably differ so much that when any methods ...
Björn's user avatar
  • 35.2k
1 vote
Accepted

Is it possible to have exactly identical output of random effects and fixed effect models in a network meta-analysis?

Firstly, it is pretty dubious to exclude studies, because their results mismatch your model. If the studies fit all your inclusion criteria, I suspect many people will feel uncomfortable about ...
Björn's user avatar
  • 35.2k
1 vote
Accepted

Reference request: initializing big neural networks with small neural networks

This paper, its bibliography, and the papers citing this paper will be a good coverage of the topic. Yoshua Bengio, Pascal Lamblin, Dan Popovici, Hugo Larochelle. "Greedy Layer-Wise Training of Deep ...
Sycorax's user avatar
  • 94.1k
1 vote

INDIRECT COMPARISONS

Comparing the odds ratios vs., say, a placebo is effectively a network meta analysis. It is simply one with extra many unverifiable and likely partially unreasonable assumptions. E.g. differences in ...
Björn's user avatar
  • 35.2k
1 vote

Network meta-analysis of correlation coefficients: a logical paradox?

Check "Exploring the use of network meta-analysis in education: examining the correlation between ORF and text complexity measures", this is closely correlated.
Jianing's user avatar
  • 11
1 vote
Accepted

P value out of pairwise random effects network meta analysis

P values can be derived by n.compl$pval.random
Rotterdam's user avatar
  • 119
1 vote

Is there a frequentist approach to Lu & Ades network meta-analysis model?

YES, there is a metafor solution for such a problem. However, since you are interested in network meta-analysis techniques, I want to point out some other references, since NMA is very active topic ...
Burak's user avatar
  • 51
1 vote

Is there any meaningfully robust approach to conduct a network meta-analysis of diagnostic test accuracy studies?

So this does not go unanswered here, based on comments from @GGA and from the OP's further research, are some references which the OP edited into the question as an update. Upon feedback from GGA ...
mdewey's user avatar
  • 18.4k
1 vote
Accepted

Multilevel Meta-analysis with several treatments

In the years since this question was asked theory and practice have advanced and the current answer would be that this is an example of network meta-analysis also known as multi-treatment comparison. ...
mdewey's user avatar
  • 18.4k

Only top scored, non community-wiki answers of a minimum length are eligible