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Can MANCOVA be applied for the following parallel factorial trials?

Good morning everyone, I have a question about the validity of MANCOVA for a project. I have a factorial experiment to optimize removal efficiency "Y", considering two factors (velocity &...
Win Yang's user avatar
1 vote
0 answers
29 views

Nested design with fixed and random effects: Is my R model correct?

I am trying to analyze a nested experimental design in R, but I am unsure whether I am approaching it correctly. I have a following data: Set Sample Repet. Response 1 1 1 y1 1 1 2 y2 1 2 1 y3 1 2 ...
Carrot's user avatar
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0 votes
0 answers
11 views

Can I use only the block section of a center composite design for optimisation?

So I designed an experiment with 6 variables to run sequentially in a supposed closed environment automatically. However during the switch from different blocks, something went wrong and now only the ...
ddkking's user avatar
1 vote
1 answer
41 views

What's the main effect for a factor?

this is my first question on here. To add a little context: I'm studying the design of experiments and I'm having trouble with the part on the main effects of the factors. I understood that if you ...
user424762's user avatar
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0 answers
28 views

Dunnett's test for comparisons with Control - how to conduct ANOVA for 2 factors, as well as adjusting for different experimental designs?

From what I understand, before we conduct Dunnett's test for comparisons of treatments to a Control, we have to do ANOVA. However, for a 2-factor experiment, there seem to be a lot of problems to me. ...
MD P's user avatar
  • 53
3 votes
1 answer
197 views

Reduce the model sequentially

I was given an ANOVA table and asked to reduce the model sequentially. I searched the online resources say: When reducing the model sequentially, you typically start by assessing the significance of ...
Matata's user avatar
  • 669
1 vote
1 answer
161 views

How to code a lme, lmer, or glmer model for a split-plot design (ANOVA)?

I have a study where the initial height of seedlings were measured at year 0 and again 11 years after treatments were applied and a net change in height was recorded. I have a split-plot design as ...
kryogenic7's user avatar
2 votes
1 answer
76 views

How to consider independent samples in a mixed-design experiment?

I collected data from an experiment with a mixed-design, specifically a 2x3x4 mixed-design, where the factors are populations (2 levels), conditions for the first population (3 levels), and conditions ...
Andrea Gulli's user avatar
1 vote
0 answers
85 views

What do you think of this analysis for a small dataset with a weird experimental design?

I have a very small dataset (n<30) that is divided in 3 groups: healthy controls, patients with condition A, and patients with condition B. I am going to do a lipidomics analysis of the samples, so ...
maglorismyspiritanimal's user avatar
3 votes
2 answers
76 views

How to construct the full interaction term for a 3-way ANOVA?

Say for the sake of the argument I have a 2x2x2 ANOVA on factors A, B, and C with levels (A1, A2), (B1, B2), and (C1, C2). Also, the design is fully balanced. I have the following 8 groupings as a ...
Matthew Graham's user avatar
2 votes
0 answers
108 views

How to conduct repeated measures Anova when there are two within factors but I am only interested in the effect of one factor?

For example, if my experimental design requires the subjects to participate in two identical sessions at two different time points(factor 1). In each session, the subjects go through all three ...
Liang Sihan's user avatar
1 vote
0 answers
35 views

Appropriate analysis for comparing treatment that is between groups to baseline collected within (multiple) groups [closed]

To help outline my question I will start with how this would normally be undertaken. Say this is animal study looking at the effects of a drug on withdrawal. The outcome in this case will be time ...
user388114's user avatar
0 votes
0 answers
42 views

How to best interpret factorial design results?

I am analysing data from a 2^3 factorial design in R. I am using blocking, and I was wondering if my reasoning is correct. I am testing reaction time in milliseconds with three factors (Type of test, ...
bob jones's user avatar
0 votes
0 answers
194 views

Is there a function in R to give the lack of fit and pure error of an ANOVA completed on a half 2^k factorial with centre points?

I have a half fraction factorial experiment for four factors, meaning I have eight experiments that I conduct. I expect that some of the responses are quadratic and not linear, thus I included centre ...
Philip de Bruin's user avatar
1 vote
1 answer
54 views

Experimental design with two factorial treatment and blocks of the treatment combination

I am going to do an experiment with planting seeds involving 2 factorial treatments. There are 4 families of seeds: F1, F2, F3, F4 and 3 foliar seed treatments: T1, T2, T3. There will be 160 seeds for ...
Sylvia Anderson's user avatar
1 vote
0 answers
29 views

How to combine within-subject score for between analysis when there is no within ID

I was task with analyzing some within/between-subject data, but my current guess is that I have no way of analyzing a combined within-subject score since an identifier/ID is missing. Is there a ...
MaxW's user avatar
  • 11
1 vote
0 answers
37 views

Between subject design, spread over multiple days

We have a between subjects design, testing for the impact of aesthetics on occupant satisfaction. Intervention is carpets vs no carpets. The people participating in each leg (intervention vs control) ...
Asit Mishra's user avatar
2 votes
0 answers
37 views

Whats the model of this experiment

$36$ blood samples are collected at random from a blood bank and $6$ samples are sent to $6$ laboratories for studies. The assignment of each sample to each laboratory is random. A friend of mine told ...
Jonathan Baram's user avatar
1 vote
1 answer
81 views

Experiment design - response variable is a sum over a period, low power

I would like to run a statistically rigorous experiment, similar to that of an E-commerce A/B test. I want to create a checkerboard of time periods where I alternate between treatments A and B. ...
wahsmail's user avatar
3 votes
3 answers
677 views

What does the phrase "adjusted by" mean?

"Matching of one group with specific exposures or outcome with a comparable group is frequently used in medical research to investigate the association between exposure and outcome." Ref ...
abc's user avatar
  • 1,831
3 votes
1 answer
179 views

What kind of study design is this and what kind of statistical analysis should be suitable?

I plan to conduct a study in which respondents will be asked to solve total 6 puzzles together. Is there a specific study design (name) for this? The scenario would be: First, ...
jquery404's user avatar
1 vote
1 answer
1k views

How to do pairwise comparisons for Kruskal Wallis test?

If the null hypothesis in the Kruskal Wallis test is rejected, How can we perform pairwise comparisons? Can we apply Dunnett's Test for that?
san's user avatar
  • 11
2 votes
0 answers
29 views

How to study the impact of time in a mixed-factorial design?

I ran a study to compare 2 different computer interfaces (say A and B) meant to be used in an unfamiliar environment. I want to compare: How much effort participants took to complete a certain task ...
Janet Johnson's user avatar
1 vote
0 answers
54 views

What layout is this?

A fleet of electric vehicles are to be investigated for the mileage performance per charge. Four vehicles have been chosen randomly from the fleet and four observations of miles were made for each ...
Yihi's user avatar
  • 11
0 votes
2 answers
814 views

Two way ANOVA unbalanced and nested TYPE III. Significant results

I have an unbalanced design with nested factors. In particular, the nested factor is obesity, with levels: of obese and nonobese. The other factor is group: women with syndrome, control women, and ...
Edmond Geraud Aguilar's user avatar
1 vote
1 answer
236 views

low sample size experimental design, t-test vs one way ANOVA

I'm designing a biological experiment wherein the sample size is very limited, as each sample is very hard to get. Moreover, I need to have 4 independent groups, each receiving a different treatment. ...
MCK's user avatar
  • 73
1 vote
0 answers
168 views

2x2 Repeated measures ANOVA gives DIFFERENT result in R and SPSS? (Same type of sums/data/analysis) Anyone know why?

Reposting this because I fixed the formatting to see if someone can actually provide a solution for this problem. I have a study design in which I am carrying out a 2x2 repeated measures ANOVA in ...
Andre Dorini's user avatar
1 vote
0 answers
36 views

Suggestion Needed about Design Experiment

As a part of my coursework, I'm supposed to be designing an experiment for an online cab service provider to understand the following: Whether letting the cab driver know the drop location of the ...
IndigoChild's user avatar
0 votes
1 answer
553 views

Analysis of design of experiments with binary response

Having a hard time determining the best way to analyze this DOE, as I'm generally used to outputs in a different format and with numeric responses. I've essentially got 2 variables at 3 levels and a ...
tastycanofmalk's user avatar
0 votes
0 answers
70 views

Is it appropriate to use difference scores in this context?

I am trying to compare the level of rating accuracy of two groups of participants (say Sample A and B). The study design is as is: I asked a consumer panel to rate how much they liked three products. ...
Theo's user avatar
  • 1
1 vote
1 answer
40 views

imbalanced experiment group design

I am trying to decide if I can use an univariate GLM model in SPSS with factors of cause, side and tool with the sample size distribution as below. Ideally, tool should be added as a random factor ...
PhDDhP's user avatar
  • 21
1 vote
1 answer
59 views

In a 2-Factor Repeated Measures design, Why do the ANOVA Expected Mean Squares have the values that they do?

I am studying experiment design, and I am trying to understand why certain designs have the Expected Mean Squares that they do. Today, I want to ask about a particular design: the 2-Factor Repeated ...
Chris Science's user avatar
0 votes
0 answers
194 views

Using the IQR method to filter outliers in experimental research, by group or as a whole?

In my current dataset (results from a factorial ANOVA), I know I have outliers (due to qualitative comments participants wrote during an online experiment), thus I'd like to do a filtering process to ...
JoeyyyFunk's user avatar
0 votes
1 answer
168 views

Unbiased Estimator for Mean Response to Treatment

$\newcommand{\eps}{\varepsilon}\newcommand{\szdp}[1]{\!\left(#1\right)}$ Problem Statement: Consider the following model for the responses measured in a randomized block design containing $b$ blocks ...
Adrian Keister's user avatar
1 vote
0 answers
158 views

How do I write sum of squares and degrees of freedom for multiple Latin squares put together?

I have notes from my professor in which a Latin square model ($s$ treatments in an $s \times s$ square) is described as follows: \begin{align*} Y_{ijk} &= \mu + \alpha_i + \beta_j + \gamma_k + \...
Novice's user avatar
  • 601
0 votes
0 answers
145 views

How to choose the right analysis for a partially nested design?

I am not even sure if it is appropriate to call this scenario a partially nested design, but I settled for it for lack of a better term. My design is similar to the following in terms of its overall ...
Freya's user avatar
  • 165
2 votes
1 answer
652 views

Deriving the expectation of SSE in randomized block design

I am trying to derive the expectation of the $\operatorname{SSE}$ in a randomized block design, $\mathbb{E}(\operatorname{SSE})$, with $$\operatorname{SSE} = \sum_{i=1}^b \sum_{j=1}^k(y_{ij} - \...
David's user avatar
  • 51
0 votes
1 answer
143 views

ANOVA or T-test for multiple groups, each group with a set of observations?

Can someone please advise on which sort of experiment or test I should run for the following. I want to know which messages would potentially resonate more within a population. I have conducted ...
Zazu's user avatar
  • 3
-1 votes
1 answer
655 views

How do I derive the Sum of Squares sums for an arbitrary ANOVA?

I know it is possible to derive the Sums of Squares sums for a simple one-way CRD ANOVA. It is done by substituting the treatment factors into the total SS equation, then squaring, eliminating terms ...
Chris Science's user avatar
2 votes
1 answer
272 views

Why is it acceptable to use the Sum of Squares of an Interaction as the Sum of Squares Error in a Randomized Complete Block Design?

Take for example the RCB design [Y = I + B + F + E], where... Y is the response I is the overall intercept B is a blocking factor with two levels F is a treatment factor with two levels E represents ...
Chris Science's user avatar
0 votes
0 answers
118 views

Analysis sense check: preregister planned contrasts which we wish to conduct even if associated ANOVA is nonsignificant?

I could use a sense check on my analysis plan for an experimental study which has not yet been run; I will preregister it once I am confident that it is reasonable. There are seven between-...
Gabriel's user avatar
  • 763
0 votes
1 answer
63 views

Different ANOVAs per species for same variable; how to proceed if only some species hold non-normal data

I am conducting two-way ANOVAs to determine if plant height (mm) is affected by treatment (3 water regimes) in different growth medium types (2). I am also interested in the interactions that may ...
Green's user avatar
  • 91
2 votes
0 answers
53 views

How to do statistical analysis on continuous group? Multinomial regression?

I am looking for suggestions on statistical methods for the following study design. We have one control group and four treatment groups of mice. Sample size is 6 mice per group. The number of ...
Tan's user avatar
  • 1,499
0 votes
1 answer
43 views

Causality comes form experiment manipulation or statistical calculation?

It is known that "Regression can only imply correlation but not causality" But whether a research can draw their variables to causality relationship is somewhat determined by whether the ...
S.F. Yeh's user avatar
0 votes
1 answer
3k views

Two factor ANOVA with blocking

I am conducting an RCBD experiment in which I have Treatment A (with 5 levels) and Treatment B (two levels). It is also being done in 3 separate locations (3 blocks). My question is, how can I do the ...
CBR's user avatar
  • 3
2 votes
2 answers
475 views

Prove two orthogonal contrasts are statistically independent

Linear combination $C=\sum_{i=1}^{n} a_i \bar{X}_i$ is called a (estimated) contrast if $\sum_{i=1}^{n} a_i=0$. Two contrasts are called orthogonal if $\sum_{i=1}^{n} a_i b_i = 0$; simplest example ...
Esmailian's user avatar
  • 604
1 vote
2 answers
982 views

What statistical test is appropriate for a pretest/posttest experimental/control group study?

I thought this would be a relatively straightforward question, but I'm having difficulty finding a decisive answer. Let's say I'm planning to run a study to test the effectiveness of a new type of ...
new_to_research's user avatar
0 votes
0 answers
60 views

Ensuring that sequence of repeated trials does not bias result

Imagine the following experimental design: You have four conditions, A,B,C and D, regarding an online platform. Conditions A,B,C have a different feature enabled that you want to compare and D has ...
anastluc's user avatar
1 vote
1 answer
75 views

Derive $E(MS_A)$ in design of experiments

Prove that $$ E(MS_A) = E\left[\frac{SS_A}{a-1}\right] = \sigma^2 + \frac{bn \sum_{i=1}^{a} \tau_i^2}{a-1}. $$ Context. In Design and Analysis of Experiments, suppose you're doing a factorial design ...
Sigma's user avatar
  • 569
1 vote
0 answers
16 views

Between or within subjects?

So I have a 2x3 design with two categorical IVs, one is Country, the other is Message type (type A, type B, and control). I've found published studies with very similar design that do both in between ...
Abc's user avatar
  • 11

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