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How to do pooled meta analysis of single arm studies with continous data (pre-post intervention) in R?

I tried to do meta analysis of single arm studies (without control) using R studio, but I still can't find how to do the pooled analysis. I only have the mean and SD from pre treatment and mean with ...
Iskandar's user avatar
0 votes
1 answer
31 views

What is the relationship between OR, se, and CI

Apologies if this is a duplicate question, but I have been unable to find a clear answer. What is the relationship between Odds Ratio, standard error, and confidence intervals? I try to do a meta-...
user447683's user avatar
1 vote
0 answers
31 views

Wald test with permutation standard error?

Many statistical tests are based on a Wald-like z-statistic: $z = \frac{\hat{\theta} - \theta_0}{\text{SE}(\hat{\theta})}$ where $\theta$ is the parameter of interest, $\theta_0$ is the value under ...
jarbet's user avatar
  • 429
0 votes
1 answer
29 views

How to obtain one study effect from several within-study effects?

I want to do a narrative review (as a meta-analysis is not possible), and I want to conclude per study whether the predictor was significant yes/no. However, studies have several effect sizes per ...
user447683's user avatar
3 votes
1 answer
94 views

Stouffer's Method: Restriction on underlying hypothesis tests producing p values?

When using Stouffer's method to combine p values, they first have to be converted to z scores. Does this mean that p values that are derived for example from a permutation test are not valid inputs, ...
user451809's user avatar
0 votes
2 answers
45 views

Pre-post design (no control) at baseline and multiple follow up times (Meta analysis)

I am working on a meta-analysis project and need advice on choosing the right statistical method. We have access to around 18 publications. The design is similar to pre-post treatment design (no ...
shian's user avatar
  • 11
3 votes
1 answer
58 views

Different results meta vs metafor for three-level meta-analysis of proportions

The R package “meta” has a function “metaprop” for meta-analysis of proportions and the argument “cluster” allows for three-level meta-analyses to be fitted. The R documentation (version 8.0-1) ...
Mark O'Donovan's user avatar
3 votes
1 answer
130 views

Wilcoxon Matched-Pair Signed-Rank and Correlation (Pearson, Spearman, or Kendall) [closed]

According to the publication Extracting Pre-Post Correlations for Meta-Analyses of Repeated Measures Designs https://matthewbjane.quarto.pub/pre-post-correlations/ , if the value of the t-statistic ...
elisa's user avatar
  • 155
0 votes
0 answers
17 views

How can one perform meta analysis on multiple studies that report paired t test results (with no control group)?

I would like to conduct a meta analysis on studies that adopt a pre post study design with no control group - i.e. all studies report paired t test results based on one sample (same sample within ...
Vivian's user avatar
  • 1
1 vote
1 answer
75 views

Choose the right Statistical test in my case

I have a survey dataset where each participant answered 20 unique questions. I want to analyze the data statistically but am unsure which test to use: ANOVA, repeated measures ANOVA, or mixed-effects ...
MexcelsiorB's user avatar
1 vote
1 answer
9 views

Include two groups post-test design study for meta-analysis pool?

I am new to meta-analysis and currently trying to find effect of intervention on service users. Most of the studies that I found were RCTs or quasi-experimental studies with 2 groups pre-post test ...
Kwok's user avatar
  • 11
1 vote
0 answers
28 views

Performing within-group meta-analysis without access to correlation coefficient r values [duplicate]

The idea is to perform a meta-analysis of single arm studies of an intervention in which there is a baseline measurement and post intervention measurement of a continuous outcome variable. The outcome ...
Ajaytobin's user avatar
0 votes
0 answers
17 views

How can I assume covariance (rho) between two psychiatric disorders for multivariate meta-analysis

I want to do a multivariate meta-analysis, as I have several effect sizes per study. For example, I want to investigate the risk (Odds Ratio) of Conduct Disorder (CD) and Oppositional Defiance ...
user447683's user avatar
0 votes
0 answers
24 views

Meta Analysis effects size calculation with multiple explanatory and response variables

Working in R. I've a data set which contains 60+ studies and 200+ sites. I'm wanting to calculate effect size (Hedges G') of each explanatory variable on each of my response variables. Data were ...
Thomo's user avatar
  • 1
0 votes
1 answer
23 views

Correlation value for calculating the variance of effect size (mean differences)

This is the Stat question I’m currently conducting a meta-analysis that primarily uses within-subject/repeated measures row mean difference as the effect size. In a referenced study, data and code ...
shian's user avatar
  • 11
7 votes
2 answers
516 views

Can I pretend that Spearman's = Pearson's correlation coefficients for meta analysis?

How legitimate it is to pretend that Spearman correlations are Pearson correlations? I am currently working on a systematic review and meta-analysis examining the correlation of Test A with Test B (...
helplessstudent147's user avatar
0 votes
1 answer
97 views

Back-transformation of Freeman-Tukey transformed incidence rates (in metafor)

Problem description I am conducting a meta-analysis of recurrence rates after surgery for different treatments of the same disease using the metafor package, but I ...
Marcel's user avatar
  • 81
0 votes
0 answers
45 views

Mean difference (continious data) (in meta analysis) (Within-group unstandardized or standardized mean differences)

I am working on a meta-analysis project and I am completely new to this topic, so any advice would be highly appreciated. Specifically, if you could provide a reference or code in R, that would be ...
elisa's user avatar
  • 155
0 votes
0 answers
33 views

what is the appropriate risk of bias assessment tool for within-subject experimental designs?

I'm working on a systematic review in which the vast majority of the included studies are using a within subject design, where all of the subject perform one or more tasks in one condition, and then ...
kinbeat's user avatar
  • 85
0 votes
0 answers
15 views

How to calculate a combined odds ratio for a single study

I am conducting a meta-analysis where the majority of my papers report M and SD and so I am using SMD as my effect size. I have one study which presents the odds ratio, so I am hoping to convert this ...
Guestuser156's user avatar
2 votes
0 answers
16 views

Which estimator to choose for meta-analysis^ REML or CR2 with Wild Bootstrap?

I am following the following book: https://bookdown.org/MathiasHarrer/Doing_Meta_Analysis_in_R/multilevel-ma.html I can't choose which estimator to choose: REML or CR2 with Wild Bootstrap. Or maybe ...
YuliaM's user avatar
  • 21
3 votes
1 answer
90 views

All correlations meta-analysis

I am new with MetaSEM. I am trying to fit a simple meta-analysis (I just want to analyse 2 correlations; see Figure). Here you can find the code that I am using with some simulated data but if there ...
JuanJMV's user avatar
  • 73
0 votes
0 answers
45 views

Different results using rma.mv: Mods vs. Subset

I am conducting a three-level meta-analysis in R using metafor. While computing a subgroup analysis I noted that the assumed summary effect of one subgroup differs from the one I would get while doing ...
hans_peter's user avatar
0 votes
0 answers
27 views

Meta-analysis of ROC areas with missing confidence interval

I am performing a meta-analysis of a diagnostic score going from 0 to 10 based on 30 reports. For each report I have data on number of false/true positive/negative patients for one and in some cases ...
Roland's user avatar
  • 301
1 vote
0 answers
43 views

Oddly large coefficients in meta-regression with correlated and hierarchical effects

I am performing meta-regression to investigate the effect of participant characteristics and study characteristics on the incident rate ratio (IRR) estimates. I have data from 10 studies, each ...
Trang Hien's user avatar
0 votes
0 answers
22 views

Are Subgroup-analyses in Metafor two-tailed?

this is probably a really obvious question, but I just want to make sure I interpret everything correctly. I am conducting a three-level meta-analysis on experimental studies in R using metafor, when ...
Lea's user avatar
  • 1
1 vote
2 answers
37 views

How similar do effect sizes (Odds Ratios) be to pool them in a meta-analysis?

I am currently working on a meta-analysis on the effect of household income on depression. An optimal primary study to be included would measure participants household income and depression at ...
tsai's user avatar
  • 11
2 votes
1 answer
121 views

What approach to use when dealing with multiple types of data dependency in a meta-analysis?

I am doing a univariate meta-analysis as well as TSSEM analysis, using the Theory of planned behavior, and correlation coefficients as effect sizes, but do not know what approach is best when dealing ...
Miljan's user avatar
  • 31
0 votes
0 answers
22 views

Meta-analysis equivalent of a one-tail, one-sample t-test

I am performing a meta-analysis comparing two methods for performing a test; the traditional (TRAD) method and a new experimental (EXP) method. As a secondary analysis I want to look at the maximum ...
Braden's user avatar
  • 121
4 votes
1 answer
93 views

Correctly modelling a continuous log dose-response relationship in meta-regression for small dosages

I’m looking at the effectiveness of a type of programme that can have a range of number of sessions, 1 to 20. I start with a meta-analysis (k = 70) that tells me the average effect size for that type ...
Sam's user avatar
  • 63
0 votes
0 answers
34 views

Is there a way to convert a bayesian credible interval to standard deviation?

I am conducting a meta-analysis and one of the included studies only provides as a measure of dispersion the 95% credible intervals, I would like to know if there is a way to convert it to standard ...
Mariano Gallo Ruelas's user avatar
0 votes
0 answers
16 views

Effect Size Calculation from 2-way ANOVA results: Meta-analysis

I am currently extracting data for a meta-analysis on continuous outcomes. I am extracting means and standard deviations for two separate groups (patients and controls) and will later calculate ...
SilvaC's user avatar
  • 542
0 votes
0 answers
25 views

Correlation index (r) in matched pair meta-analysis

CONTEXT: We are to perform a meta-analysis of the difference between a and b. In all the collected studies, a and b are the mean times to failure in seconds of two different tasks performed by the ...
CrappyCoder's user avatar
0 votes
0 answers
23 views

Calculating Confidence Intervals for Odds Ratios Based Only on Odds Ratio and Total Sample Size [duplicate]

I'm running a meta-analysis, and many studies report only the total sample size and odds ratio, which complicates calculating the sampling variances. I could use the odds ratio, total sample size, and ...
shira's user avatar
  • 1
0 votes
0 answers
12 views

Meta-analyses with effect sizes from observational data - how to handle mutiple results from one study

I am hoping to perform my first meta-analysis using adjusted odds ratios and confidence intervals (using Stata). I am specifically looking at one class of groups that has two subclasses. I have these ...
user427110's user avatar
5 votes
1 answer
114 views

How to report the between study variance through tau2 for vaccine effectiveness using R's metafor?

My colleague and I have been performing a meta analysis using R's metafor package and the rma.uni function to estimate pooled ...
Stefan Verweij's user avatar
0 votes
0 answers
26 views

Can someone help me understand the overall comorbidity in this OCD meta analysis?

I writing an essay regarding the prevalence of ocd in law students and I wanted to assess the overall comorbidity that ocd has So I found a very good meta analysis regarding ocd and it's comorbidities ...
Xin Feng's user avatar
2 votes
1 answer
44 views

Meta-analysis vs mixed-effect model to estimate effect size

I have data from three previous experiments and I want to use them in a power analysis to calculate the required sample size for a new study. A classical way to do this, is to make a meta analysis to ...
PuzzledBiologist's user avatar
3 votes
1 answer
72 views

Two ways of meta-analysis: Which one is preferred?

Suppose that I have $k=1, 2, 3...K$ studies with the same set of a continuous independent variable $Y$ and dependent variables $X$. The effect between studies may be different, and I want to run a ...
processing_statistician's user avatar
1 vote
1 answer
26 views

Coding for meta-analysis

When coding studies to be included in a meta-analysis (meta-regression) not all of them will have the same covariates. My question deals with the following situation. One study has age and sex. One ...
nsmiceli's user avatar
1 vote
0 answers
29 views

Meta analysis with overidentified 2SLS estimates

To meta analyze estimates of some parameter $\theta$, we assume we have estimates $\hat{\theta_i} = \theta_i + \epsilon_i$, where $\theta_i \sim G(\theta)$ and $\epsilon_i \sim N(0, \sigma_i^2)$. If ...
karthikt's user avatar
1 vote
0 answers
22 views

Rescale measures of association for meta-analysis (e.g., log-transformed independent variables)

I am carrying out a meta-analysis of studies evaluating the association between blood levels of specific environmental pollutants and health outcomes (binary). Some studies reported OR/RR/HR for ...
msas's user avatar
  • 11
2 votes
1 answer
44 views

How to handle dependent effect sizes in meta-analysis with a single control group?

I am conducting a meta-analysis and need advice on extracting effect sizes from studies where multiple treatment groups are compared to a single control group. Specifically, I am dealing with standard ...
tomas.rosa's user avatar
6 votes
1 answer
435 views

Related low p-values that do not meet statistically significant thresholds

If I were to have multiple related measures, each with "low" p-values that do not quite meet the threshold of significance, could the fact that multiple measures produce a general trend with ...
Jaxton Winder's user avatar
1 vote
1 answer
47 views

Conducting a network meta-analysis in R - inputting dichotomous data

I am looking to conduct a meta-analysis in R using {netmeta}. However, my outcome of interest is a little bit complex and would appreciate advice in how best to enter it into the dataset. I am looking ...
emmz's user avatar
  • 11
1 vote
1 answer
116 views

How to find difference between two hazard ratios (ratio of hazard ratios)

I am reading a meta-analysis and in this paper the authors somehow compared HR from two groups with different treatments in each study. As I know, we can compare outcomes from two groups with ...
reress's user avatar
  • 53
4 votes
2 answers
146 views

Analyzing an experiment which consists of many "small" experiments

Consider the following setting: I am trying to choose between two bakers for my new bakery, Baker A and Baker B. The way that I am evaluating them is on a set of different cakes on the menu: Cake 1, ...
gaussiandynamics's user avatar
0 votes
1 answer
59 views

Robust Variance Estimation or Cluster Wild Bootstrapping on a multivariate meta-analysis

Cliffnotes Can I use RVE or cluster wild bootstrapping in meta-analytic models that are not meta-regression? Question I am conducting a three-level meta-analysis looking at the effects of a particular ...
Max Moser's user avatar
0 votes
0 answers
29 views

Conditional Logit Model - Utility Structural Estimation - Meta Analysis

I am performing a structural estimation of an utility function across several databases (from distinct articles) using McFadden (2001) framework (see reference). Each article's database includes N ...
RobM's user avatar
  • 1
1 vote
1 answer
142 views

Understanding correlated and hierarchical effects models in meta-analysis

I am doing a three-level meta-analysis, and I want to compare a three-level correlated and hierarchical effects model where effects are nested between-studies to a two-level model where variance at ...
Max Moser's user avatar

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